Results 271 to 280 of about 32,560 (347)

ISUP grade upgrade prediction after radical prostatectomy: Role of Luteinizing Hormone to Testosterone ratio

open access: yesBJUI Compass, Volume 6, Issue 7, July 2025.
Abstract Purpose This study aimed to evaluate the predictive value of the luteinizing hormone to testosterone (LH/T) ratio in postoperative International Society of Urological Pathology (ISUP) grade upgrading following radical prostatectomy. Materials and Methods Clinical data from 503 patients who underwent radical prostatectomy (RP) at Jiangsu ...
Zhihua Pan   +5 more
wiley   +1 more source

A Case of Paratesticular Cellular Angiofibroma Presenting as Inguinoscrotal Hernia

open access: yesClinical Case Reports, Volume 13, Issue 7, July 2025.
ABSTRACT Cellular Angiofibroma (CAF) is a rare and benign neoplasm with a good prognosis. Diagnosis of CAF can be challenging due to its nonspecific clinical and radiological features, which can often lead to a misdiagnosis, as in our case of a 77‐year‐old male.
Hamza Arif   +5 more
wiley   +1 more source

Bilateral Seminoma in a Pediatric Patient With a History of Cryptorchidism: A Case Report. [PDF]

open access: yesCureus
Rochel-Perez EA   +5 more
europepmc   +1 more source

Primary Mediastinal Germ Cell Tumor With Bone Marrow Infiltration: A Case Report and Literature Review

open access: yesCancer Reports, Volume 8, Issue 7, July 2025.
ABSTRACT Introduction Bone marrow infiltration is a rare presentation in patients with extragonadal germinal cell tumors (EGGCTs). We report a case of primary mediastinal germ cell tumor presenting with bone marrow metastases. Case Presentation A 28‐year‐old male patient was admitted to Instituto Nacional de Enfermedades Neoplásicas with superior vena ...
Patricia Rioja   +5 more
wiley   +1 more source

First‐in‐Human Single and Multiple Ascending Dose Studies of Balinatunfib, a Small Molecule Inhibitor of TNFR1 Signaling in Healthy Participants

open access: yesClinical Pharmacology &Therapeutics, Volume 118, Issue 1, Page 164-176, July 2025.
Oral small molecule inhibitors of tumor necrosis factor alpha (TNFα) are emerging as attractive therapeutic agents for the treatment of various autoimmune diseases. Balinatunfib (SAR441566), a novel oral inhibitor of tumor necrosis factor receptor 1 (TNFR1) signaling, changes the configuration of the soluble TNFα (sTNFα) trimer and prevents its ...
Nassr Nassr   +12 more
wiley   +1 more source

Deubiquitinase TRIM44 Promotes Autophagy‐Mediated Chemoresistance in Diffuse Large B Cell Lymphoma

open access: yesHematological Oncology, Volume 43, Issue 4, July 2025.
ABSTRACT Diffuse large B cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin lymphoma. Tripartite motif containing 44 (TRIM44) belonging to the TRIM family, is involved in tumor development and is highly expressed in a variety of tumors. However, the role of TRIM44 in DLBCL remains undefined. Gain and loss‐of‐function studies were performed
Yan Wang   +7 more
wiley   +1 more source

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