YKT6 Is Essential for Male Fertility by Promoting Meiosis Progression During Spermatogenesis of Mice
Specifically ablating Ykt6 in pre‐meiotic germ cells and meiotic spermatocytes leads to complete sterility and meiotic arrest in conditional knockout male mice. YTK6 is required for stabilising intercellular bridges between spermatocytes due to its key role in maintaining protein homeostasis and vesicular transport‐dependent functions in spermatocytes,
Jie Cen+8 more
wiley +1 more source
Fertility preservation for a 13-year-old male with relapsed osteosarcoma
Many benign and malignant conditions require gonadotoxic treatment regimens that may threaten a child or adolescent's future fertility. Both males and females who have undergone gonadotoxic regimens are more likely to be infertile or have difficulty ...
Courtney J. Harris+6 more
doaj
Stepwise mini-incision microdissection testicular sperm extraction in NOA patients with a history of cryptorchidism: a case-control study. [PDF]
Xu S+9 more
europepmc +1 more source
The impact of early testicular sperm extraction or cryopreservation on the outcome of intracytoplasmic sperm injection--a randomized controlled study. [PDF]
Martha Dirnfeld+8 more
openalex +1 more source
Many fishes can change their sex. The remarkable example, Lubricogobius exiguus, is a goby that can undergo bidirectional sex change with hermaphroditic gonads, containing both developed ovaries and testes (simultaneously hermaphroditic phase gonad). Based on field observations, we demonstrate that the goby experiences frequent social changes, such as ...
Takumi Oyama+2 more
wiley +1 more source
Serum testosterone levels in patients with nonmosaic Klinefelter syndrome after testicular sperm extraction for intracytoplasmic sperm injection [PDF]
Hiroshi Okada+5 more
openalex +1 more source
Adverse impact of acute Toxoplasma gondii infection on human spermatozoa
Toxoplasma gondii tachyzoites injected intraperitoneally crossed the blood‐testes barrier, appearing in testes/epididymis by day 6 post‐infection. In vitro exposure caused increased sperm necrosis/apoptosis and structural damage to heads/tails. Immunofluorescence and SEM revealed tachyzoites attaching to sperm tails, inducing twisting/detachment, and ...
Lisbeth Rojas‐Barón+11 more
wiley +1 more source
A Prior History of Cryptozoospermia Is Associated with a Significantly Higher Chance of a Successful Microdissection Testicular Sperm Extraction Compared to Non-Obstructive Azoospermia. [PDF]
Wren J+7 more
europepmc +1 more source
Testicular Sperm Extraction (TESE) and Intracytoplasmic Sperm Injection (ICSI) in Hypogonadotropic Hypogonadism with Persistent Azoospermia After Hormonal Therapy [PDF]
Marcos Meseguer+4 more
openalex +1 more source
Ceratonia siliqua Protects Testicular Tissue in Ischemia/Reperfusion Injury
ABSTRACT Objectives Testicular torsion is a urological emergency with a risk of resulting in loss of testicular function due to ischemia/reperfusion injury (I/R) injury caused by oxidative stress. Ceratonia siliqua is known to decrease oxidative stress in urological pathologies. We investigated the protective effects of C.
Şahika Yardim+6 more
wiley +1 more source