Results 61 to 70 of about 875,892 (345)

Nurr1 Orchestrates Claustrum Development and Functionality

Advanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan, Andrew G. Newman, Pauline Lange, Susanne Müller, Marco Foddis, Stefan Paul Koch, Philipp Böhm‐Sturm, Maron Mantwill, Carsten Finke, Penghui Deng, Melissa Long, Dietmar Schmitz, Victor Tarabykin   +12 more
wiley   +1 more source

Assurance Views of Testimony [PDF]

, 2019
Assurance theories of testimony attempt to explain what is distinctive about testimony as a form of epistemic warrant or justification. The most characteristic assurance theories hold that a distinctive subclass of assertion (acts of “telling”) involves ...
Nickel, Philip J.
core   +1 more source

Investigating Mitochondrial Viscosity in Ferroptosis‐Mediated Drug‐Induced Liver Injury using a Double‐Targeted Strategy

Advanced Science, EarlyView.
Utilizing a mitochondrial double‐targeted strategy, a novel near‐infrared fluorescent probe (FTZ‐2) is established for monitoring viscosity variations in ferroptosis‐mediated drug‐induced liver injury. In summary, this work provided a practical strategy for the early diagnosis and evaluation of liver injury.
Yongqing Zhou, Yan Wang, Bing Huang, Hosoowi Lee, Mei Yan, Juyoung Yoon   +5 more
wiley   +1 more source

Multi‐Dimensional Acoustic Cascaded Holographic Encryption with Instantaneous Visual Decryption via Particle Manipulation

Advanced Science, EarlyView.
Acoustic holograms act as key tools for information encryption, yet current schemes limit encryption dimensionality/security and require time‐consuming decryption. A compact device integrates multi‐dimensional cascaded acoustic holography with particle manipulation, employs extra secret keys, enables rapid decryption, and is validated via 1D/2D/3D ...
Qin Lin, Feiyan Cai, Yunqing Liu, Zejiao Zhou, Jiayang Li, Rujun Zhang, Hongpeng Chen, Hairong Zheng, Huailing Zhang   +8 more
wiley   +1 more source

Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy

Hepatology, EarlyView., 2022
Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann, Marti Cabanes‐Creus, Moritz Ertelt, Renina Gale Navarro, Julie Lucifora, Qinggong Yuan, Karin Nien‐Huber, Ahmed Abdelrahman, Xuan‐Khang Vu, Liang Zhang, Ann‐Christin Franke, Christian Schmithals, Albrecht Piiper, Annabelle Vogt, Maria Gonzalez‐Carmona, Jochen T. Frueh, Evelyn Ullrich, Philip Meuleman, Steven R. Talbot, Margarete Odenthal, Michael Ott, Erhard Seifried, Clara T. Schoeder, Joachim Schwäble, Leszek Lisowski, Hildegard Büning   +25 more
wiley   +1 more source

Section 1983: Absolute Immunity for Pretrial Police Testimony [PDF]

, 1987
This Note discusses the development of the Supreme Court\u27s approach to section 1983 immunity for trial witnesses. Central to this discussion is an overview of the history of common-law immunities for government officials, the history and purpose of ...
Kaufman, Jack
core   +1 more source

Voxel‐SLAM: A Complete, Accurate, and Versatile Light Detection and Ranging‐Inertial Simultaneous Localization and Mapping System

Advanced Intelligent Systems, EarlyView.
: In this work, Voxel‐SLAM (simultaneous localization and mapping) is introduced: a complete, accurate, and versatile LiDAR (light detection and ranging) ‐inertial SLAM system consisting of five modules: initialization, odometry, local mapping (LM), loop closure (LC), and global mapping (GM), all employing the same map representation, an adaptive voxel
Zheng Liu, Haotian Li, Chongjian Yuan, Xiyuan Liu, Jiarong Lin, Rundong Li, Chunran Zheng, Bingyang Zhou, Wenyi Liu, Fu Zhang   +9 more
wiley   +1 more source

Testimony on H.R. 1915 [PDF]

, 1995
Public testimony by Prof. Briggs given before the Subcommittee on Immigration and Claims of the Committee on the Judiciary, House of Representatives, June 29 ...
Briggs, Vernon M., Jr.
core   +1 more source

Structural problems without structural solutions? Youth leaders' perceptions of their community

American Journal of Community Psychology, EarlyView.
Abstract As young people explore and reflect on the conditions of their neighborhoods and communities, they can forge a critical consciousness—merging their perspectives and analysis to direct both individual and collective actions. Photovoice is a methodological tool that allows participants to document their perspectives and analysis and discuss with
Linnea L. Hjelm, Aishia A. Brown, Benjamin W. Fisher, Alice Story, Nubia Bennett   +4 more
wiley   +1 more source

Moral testimony:

Filosofia Unisinos
According to some pessimists, trusting moral testimony is an action in which the agent does not think about moral questions by herself, and thus it is unacceptable.
Xuanpu Zhuang
doaj   +1 more source