Results 141 to 150 of about 4,573,501 (300)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Wilbert F. Snyder

open access: yes, 1995
Wilbert F. Snyder NBS: 1927-1969 B: April 19, 1904, Marion, Ohio D: February 24, 2000, Boulder, Colorado EDUCATION: North Central College, BA, 1926 University of Illinois, MA, 1927 PRINCIPAL FIELD: Radio science; calibration of acoustical and ...
National Institute of Standards and Technology
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

United States National Bureau of Standards Building and Housing Publication BH13 (Supplement)

open access: yes, 1931
Report issued by the Bureau of Standards discussing revisions and supplements made to minimum plumbing requirements for residential and commercial buildings. The revisions and supplements to previous reports are presented.
United States. Bureau of Standards.
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Clark A. Hamilton

open access: yes, 2004
CLARK A. HAMILTON NBS/NIST: 1971 - 1999 B: April 22, 1944, Rochester, New York EDUCATION: Union College, BS (Electrical Engineering), 1966 University of Rochester, MS (Electrical Engineering), 1968 University of Rochester, PhD (Electrical Engineering),
National Institute of Standards and Technology
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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