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Transdermal Testosterone

Drugs, 1998
Nightly application of testosterone transdermal (TTD) system to nonscrotal sites in men with hypogonadism results in a 24-hour serum testosterone concentration profile which mimics the circadian pattern observed in healthy young men. The system also normalises dihydrotestosterone/testosterone and estradiol/testosterone ratios and reduces luteinising ...
K J, McClellan, K L, Goa
openaire   +2 more sources

Testosterone and obesity

Obesity Reviews, 2015
SummaryTestosterone is a key hormone in the pathology of metabolic diseases such as obesity. Low testosterone levels are associated with increased fat mass (particularly central adiposity) and reduced lean mass in males. These morphological features are linked to metabolic dysfunction, and testosterone deficiency is associated with energy imbalance ...
D M, Kelly, T H, Jones
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Focusing on Testosterone

Urology, 2011
Since Huggins and Hodges first established testosterone as the principal androgenic hormone responsible for the growth of prostate cancer in 1941, lowering the circulating testosterone to surgical castration levels (
Judd W, Moul, Robert, Dreicer
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Absolute bioavailability of testosterone after oral administration of testosterone-undecanoate and testosterone

European Journal of Drug Metabolism and Pharmacokinetics, 1986
The plasma levels of testosterone (T) were measured after oral administration of 25 mg T and 40 mg testosterone-undecanoate (TU) in a group of young women by a specific radioimmunoassay. Plasma levels were compared to those after intravenous administration of 1.5 micrograms testosterone/kg to another group of young women for determination of absolute ...
U, Täuber   +3 more
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Testosterone Deficiency

The American Journal of Medicine, 2011
Testosterone deficiency (TD) afflicts approximately 30% of men aged 40-79 years, with an increase in prevalence strongly associated with aging and common medical conditions including obesity, diabetes, and hypertension. A strong relationship is noted between TD and metabolic syndrome, although the relationship is not certain to be causal.
Abdulmaged M, Traish   +3 more
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Testosterone Assays

Urologic Clinics of North America, 2022
Challenges to the accurate and precise measurement of testosterone include deficiencies in standardization, variable reference ranges, expenses related to gold standard equipment, and other challenges. Total testosterone remains the most accessible for standard laboratories, while free testosterone and bioavailable testosterone may be useful adjuncts ...
Brendan, King   +2 more
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Testosterone and Varicocele

Urologic Clinics of North America, 2016
Varicocele is defined as an excessive dilation of the pampiniform plexus. The association between varicocele and infertility has been well-established as evidenced by negative effects on spermatogenesis. Accumulating evidence now suggests that varicocele presents a pantesticular insult, with resultant impairment of Leydig cell function. The presence of
Russell P, Hayden, Cigdem, Tanrikut
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Testosterone and Frailty

Clinics in Geriatric Medicine, 1997
Although estrogen replacement therapy has become well established in the management of postmenopausal women, most physicians pay much less attention to the testosterone status of their older male patients. There is now increasing evidence that testosterone deficiency-Low Testosterone Syndrome-occurs in older men and is associated with decreased muscle ...
J E, Morley   +4 more
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Testosterone and behavior

Clinics in Geriatric Medicine, 2003
In older men and women testosterone clearly improves libido and perhaps sexual activity. A number of authors have tried to describe a set of behavioral symptoms associated with the andropause. In older women testosterone seems to decrease dysphoria. In men the effects of testosterone on mood are less clear.
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Testosterone and dyslexia

Pediatric Rehabilitation, 1997
Geschwind, Behan and Galaburda have presented empirical research which indicates an association between left-handedness, immune disorders, and learning difficulties. Moreover, they have presented an hypothesis that purports to explain these associations, i.e. the 'testosterone hypothesis'. This article seeks to show that their hypothesis cannot explain:
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