Results 11 to 20 of about 13,782 (265)

Assessing the Efficacy of Parental Testosterone Therapy in the Penis Size Before Hypospadias Surgery

Journal of Pharmacy and Bioallied Sciences
Background: Parenteral testosterone has been used to increase glans diameter and penis size before hypospadias surgery. However, the existing literature data are scarce in the Indian context.
Praveen S. Baghel, Anil Dawar, Roshan Mandloi, Sarika Rawat, Sonu Rawat   +4 more
doaj   +2 more sources

A neural circuit for sex-dependent conditioned pain hypersensitivity in mice [PDF]

Nature Communications
The neural mechanisms underlying sex-specific pain, in which males and females exhibit distinct responses to pain, remain poorly understood. Here we show that in a mouse model of male-specific pain hypersensitivity response to pain conditioning ...
Mingjun Zhang, Ziyun Ni, Jun Ma, An Liu, Ying Liu, Qianqian Lou, Wan-Ying Dong, Zhi Zhang, Juan Li, Peng Cao   +9 more
doaj   +2 more sources

Inhibitory effects of Calocybe indica macrofungi on experimental benign prostatic hyperplasia in rats [PDF]

Iranian Journal of Basic Medical Sciences, 2023
Objective(s): This study was designed to investigate the protective effects of Calocybe indica extract on testosterone-induced benign prostatic hyperplasia in rats.
Remigius Onoja, John Ihedioha, Shodeinde Shoyinka, Arinze Ezema, Nnenna Emejuo, Anthony Mgbeahuruike, Benjamin Emesiani, Wilson Obidah, Iyi Clinton   +8 more
doaj   +1 more source

Detection of Anabolic Androgenic Steroids and Steroid Esters-Comparing Dried Blood Spots Collection Devices and Urine Samples. [PDF]

Drug Test Anal
DBS (Capitainer‐B50 and Tasso‐M20) enabled detection of testosterone esters in all participants, whereas urine testing (T/E) missed cases including potential UGT2B17 del/del carriers and individuals with testosterone prescription. More AAS and steroid‐esters could be detected in Capitainer‐B50 versus Tasso‐M20.
Suominen T, von Walden J, Harju L, Pohanka A, Schulze J, Lehtihet M, Ekström L.   +6 more
europepmc   +2 more sources

Amelioratory Effects of Testosterone Propionate on Age-related Renal Fibrosis via Suppression of TGF-β1/Smad Signaling and Activation of Nrf2-ARE Signaling. [PDF]

Sci Rep, 2018
Zhang G, Kang Y, Zhou C, Cui R, Jia M, Hu S, Ji X, Yuan J, Cui H, Shi G.   +9 more
europepmc   +3 more sources

Simplified Analysis of Native Steroid Esters in Dried Blood Spots by LC-MS³. [PDF]

J Mass Spectrom
ABSTRACT Steroidal esters (e.g., testosterone, nandrolone and boldenone esters) belong to the substance class prohibited in professional sport that is particularly frequently abused due to its considerable performance‐enhancing effects. Thus, a high number of adverse analytical findings in doping controls is reported every year.
Thomas A, Thelen J, Sakellariou P, Thevis M.   +3 more
europepmc   +2 more sources

Sildenafil ameliorates leptin resistance and normalizes lipid handling in the hypothalamic and adipose tissues of testosterone-exposed pregnant rats

Heliyon, 2021
Leptin and hypothalamic-adipose lipid handling are relevant in determining the shift of metabolic activities. There are scanty findings connecting glucose dysregulation as a result of hyperandrogenism during gestation to hypothalamic-adipose axis and ...
Emmanuel Damilare Areola, Isaiah Woru Sabinari, Taofeek Olumayowa Usman, Faith Ifeoluwa Abayomi, Onyeka Onyezia, Bisola Onaolapo, Phebe Oluwaseun Adetokunbo, Olympus Oyewole Adebanjo, Funmilayo Rebecca Oladipupo, Lawrence Aderemi Olatunji   +9 more
doaj   +1 more source

Sildenafil augments fetal weight and placental adiponectin in gestational testosterone-induced glucose intolerant rats

Toxicology Reports, 2021
Testosterone induces intra-uterine growth restriction (IUGR) with maternal glucose dysregulation and oxidant release in various tissues. Adiponectin, which modulates the antioxidant nuclear factor erythroid 2-related factor 2 (Nrf2) signaling is ...
Emmanuel Damilare Areola, Ifeoluwa Jesufemi Adewuyi, Taofeek Olumayowa Usman, God’sgift Tamunoibuomi, Lucy Kemi Arogundade, Barakat Olaoye, Deborah Damilayo Matt-Ojo, Abdulrazaq Olatunji Jeje, Adewumi Oluwafemi Oyabambi, Enoch Abiodun Afolayan, Lawrence Aderemi Olatunji   +10 more
doaj   +1 more source

A systematic review of transgender male rodent model methodology. [PDF]

Animal Model Exp Med
Summary of successful transgender male rodent model methods. Testosterone enanthate or cypionate injected SC or IM once per week at 18 mg/kg in mice or 3 mg/kg in rats should effectively match naive male testosterone levels of their respective species.
Robertson K, Lane D, Donner D, Peart J, du Toit E.   +4 more
europepmc   +2 more sources

Factors determining the kinetics of a single dose of testosterone in rats [PDF]

Archives of Biological Sciences, 2012
The results from different authors regarding testosterone and cognitive research show controversial results. One of the reasons may be the form of testosterone used in the experiment.
Majzúnová Miroslava, Filová Barbora, Celec P., Hodosy J., Ostatníková Daniela, Malinová Mária   +5 more
doaj   +1 more source