Results 21 to 30 of about 13,782 (265)

Natural Sweetener Stevioside-Based Dissolving Microneedles Solubilize Minoxidil for the Treatment of Androgenic Alopecia. [PDF]

Adv Healthc Mater
This study addresses limitations of minoxidil (MXD) in treating androgenetic alopecia by using stevioside (STV) as a solubilizing agent and microneedle (MN) material. STV enhanced MXD's solubility and skin absorption, leading to improved drug delivery and significant hair regrowth in animal models, demonstrating strong potential for AGA treatment ...
Zhang J, Shao T, Li H, Zhu L, Albakr L, Wheate NJ, Kang L, Wu C.   +7 more
europepmc   +2 more sources

Effect of androgen treatment during foetal and/or neonatal life on ovarian function in prepubertal and adult rats [PDF]

, 2012
We investigated the effects of different windows of testosterone propionate (TP) treatment during foetal and neonatal life in female rats to determine whether and when excess androgen exposure would cause disruption of adult reproductive function ...
Abbott, Abbott, Abbott, Alan S McNeilly, Amanda J Drake, Anderson, Anderson, Baravalle, BARRACLOUGH, Beloosesky, BRAWER, Brawer, Carretero, Champagne, Childs, Durlinger, Faiman, Franks, Grossmann, Hillier, HIRSHFIELD, Hoepfner, Honnma, Levallet, Marie Broyde, McNeilly, Michelle Welsh, Misugi, Murray, Nelson, Nelson, Nilsson, Ota, Pepling, Pepling, Picon, Rey, Richard Sharpe, Roma, Rossetti, Scalzo, Schindler, Slob, Tetsuka, Victoria Tyndall, Webber, Welsh, Welsh, Wolf, Xia, Yan   +50 more
core   +3 more sources

Differential Effects of Neonatal Testosterone Treatment on Aggression in Two Selection Lines of Mice [PDF]

, 1992
Selection lines of mice, artificially selected for aggression based upon the attack latency score (ALS), were used. In order to determine the relative contribution of neonatal testosterone (T) in the development of aggression, we vary the plasma-T level ...
Bohus, Béla,, Compaan, Josje C.,, Koolhaas, Jaap M.,, Oortmerssen, Geert A. van,, Ruiter, Anne J.H. de,   +4 more
core   +2 more sources

Effective separation and simultaneous analysis of anabolic androgenic steroids (AAS) in their pharmaceutical formulations by a validated TLC-densitometry method

Chemistry Central Journal, 2012
Background Anabolic androgenic steroids (AAS) are widely misused for the enhancement of performance in sports. Several drugs are available that contain different combinations or individual steroids in different dosage form.
Musharraf Syed, Gulzar Umair
doaj   +1 more source

Gonadal hormones, but not sex, affect the acquisition and maintenance of a Go/No-Go odor discrimination task in mice [PDF]

, 2018
In mice, olfaction is crucial for identifying social odors (pheromones) that signal the presence of suitable mates. We used a custom-built olfactometer and a thirst-motivated olfactory discrimination Go/No-Go (GNG) task to ask whether discrimination of ...
Bass, M., Baum, Michael J., Cherry, James A., Coyne, A., Kunkhyen, T., Perez, E.   +5 more
core   +1 more source

Rodent Models of Polycystic Ovary Syndrome [PDF]

, 2013
Rodents are clearly valuable models for assessing disruption of fertility. The effects of different steroid treatments at different stages of reproductive life through from fetal to adult have been assessed for effects on fertility, ovarian morphology ...
Duncan, Colin, McNeilly, Alan S
core   +1 more source

Development and validation of HPLC-DAD methodology for simultaneous qualitative and quantitative determination of thirteen substances with a steroid structure

Biotechnology & Biotechnological Equipment, 2023
Using supplements in different sports is a common practice for many athletes. Unfortunately, the growth of this market has entailed some speculations, such as the addition of excessive doses of potentially toxic ingredients. Sometimes the doses listed on
Zdravka Zaharieva, Stanimira Atanasova, Dancho Danalev, Sirine Jaber, Tsvetelina Foteva, Veronica Nemska, Dimitar Tanev, Nelly Georgieva   +7 more
doaj   +1 more source

Abnormal infant islet morphology precedes insulin resistance in PCOS-like monkeys. [PDF]

, 2014
Polycystic ovary syndrome (PCOS) is prevalent in reproductive-aged women and confounded by metabolic morbidities, including insulin resistance and type 2 diabetes.
Abbott, David H, Dumesic, Daniel A, Grogan, Tristan, Nicol, Lindsey E, O'Brien, Timothy D, Tarantal, Alice F   +5 more
core   +3 more sources

Impact of Neonatal Manipulation of Androgen Receptor Function on Endocrine-Metabolic Programming in the Juvenile Female Rat [PDF]

, 2013
The impact of neonatal androgen receptor (AR) stimulation/blockage, due to testosterone propionate (TP)/AR antagonist treatment, on individual anthropometry and neuroendocrine-metabolic function was evaluated in the juvenile female rat. Pups (age 5 days)
Giovambattista, Andres, Ongaro, Luisina, Spinedi, Eduardo Julio   +2 more
core   +3 more sources

Effects of short-term testosterone replacement on areal bone mineral density and bone turnover in young hypogonadal males

Indian Journal of Endocrinology and Metabolism, 2012
Context: Effect of parenteral testosterone esters administration on bone-mineral density (BMD) and bone turnover in young age onset male hypogonadism is not studied in Indian subjects.
Prasun Deb, Sushil Kumar Gupta, Madan M Godbole   +2 more
doaj   +1 more source