Testosterone induces intra-uterine growth restriction (IUGR) with maternal glucose dysregulation and oxidant release in various tissues. Adiponectin, which modulates the antioxidant nuclear factor erythroid 2-related factor 2 (Nrf2) signaling is ...
Emmanuel Damilare Areola+10 more
doaj
The world's first anabolic-androgenic steroid testing trial: A two-phase pilot combining chemical analysis, results dissemination and community feedback. [PDF]
Abstract Background and Aims The clandestine production and distribution of anabolic‐androgenic steroids (AAS) poses health risks due to the uncertainty of their contents. This study aimed to test the chemical content of AAS samples and provide aggregate results back to the community, exploring how these results influenced usage decisions and risk ...
Piatkowski T+13 more
europepmc +2 more sources
Different Aspects of Letrozole Effect on Metabolism, Bone Health, Oxidative Stress and Prostate in the Intact Adult Dog. [PDF]
Letrozole increased the total antioxidant capacity and reduced malondialdehyde concentrations in both serum and seminal plasma. Letrozole increased parathormone and alkaline phosphatase levels in the serum. Letrozole decreased serum levels of IGF‐1, calcium, and 1, 25‐dihydroxy vitamin D.
Dadvand Z+7 more
europepmc +2 more sources
Abnormal infant islet morphology precedes insulin resistance in PCOS-like monkeys. [PDF]
Polycystic ovary syndrome (PCOS) is prevalent in reproductive-aged women and confounded by metabolic morbidities, including insulin resistance and type 2 diabetes.
Abbott, David H+5 more
core +3 more sources
Excessive carotid body responsiveness to O2 and/or CO2/H+ stimuli contributes to respiratory instability and apneas during sleep. In hypogonadal men, testosterone supplementation may increase the risk of sleep-disordered breathing; however, the site of ...
Tara A. Janes+6 more
doaj +1 more source
Profiling Urinary Sulfate Metabolites With Mass Spectrometry
The study of urinary phase II sulfate metabolites is central to understanding the role and fate of endogenous and exogenous compounds in biological systems.
Christopher C. J. Fitzgerald+8 more
doaj +1 more source
No effect of a high-fat diet on promotion of sex hormone-induced prostate and mammary carcinogenesis in the Noble rat model [PDF]
Results of international correlation and migrant studies suggest that dietary fat promotes carcinogenesis in hormone-sensitive sites, but this is disputed.
Benzie, IFF+4 more
core +3 more sources
Activité anti-androgénique de Leptadenia hastata (Pers.) Decne : effet compétitif des extraits aqueux de la plante et du propionate de testostérone sur des rats impubères castrés [PDF]
Anti-androgenic activity of Leptadenia hastata (Pers.) Decne: competitive effect of the aqueous extracts of the plant and the testosterone propionate on castrated immature rats.
Bayala, B.+4 more
doaj
The effect of testosterone propionate in different treatments was tested in adult male rats (250 g.) with mechanical skin experimental lesions. The whole period of cicatrization was investigated in normals, castrated and testosterone treated animals.
Fernando Ubatuba, Jorge Costa de Moraes
doaj +1 more source
Testosterone masculinizes male sexual behavior through an organizational and activational effects. We previously reported that the emission of ultrasonic vocalizations (USVs) in male mice was dependent on the organizational effects of testosterone ...
Takefumi Kikusui+8 more
doaj +1 more source