Results 51 to 60 of about 183,104 (293)

Dietary Selenium Deficiency Accelerates the Onset of Aging‐Related Gut Microbial Changes in Aged Telomere‐Humanized Mice, With Akkermansia muciniphila Being the Most Prominent and Alleviating Selenium Deficiency‐Induced Type 2 Diabetes

Aging Cell, EarlyView.
Gut Akkermansia muciniphila is enriched by dietary selenium deficiency in aged telomere‐humanized mice and counteracts dietary selenium deficiency‐induced type 2 diabetes. ABSTRACT Previous studies have shown that dietary selenium (Se) deficiency in mice reshapes gut microbiota, exacerbates healthspan deterioration (e.g., type 2 diabetes), and ...
Ying‐Chen Huang, Hsin‐Yi Lu, Li Zhang, Alicia Olivier, Tung‐Lung Wu, Chuan‐Yu Hsu, Caleb LeGrand, Huawei Zeng, Samantha Curran, Qingzhou Wang, Ramakrishna Nannapaneni, Xue Zhang, Max Ticó, Marco Mariotti, Ryan T. Y. Wu, Gerald F. Combs Jr, Wen‐Hsing Cheng   +16 more
wiley   +1 more source

Taxonomic study and partial characterization of antimicrobial compounds from a moderately halophilic strain of the genus Actinoalloteichus [PDF]

, 2011
A moderately halophilic actinomycete strain designated AH97 was isolated from a saline Saharan soil, and selected for its antimicrobial activities against bacteria and fungi.
Boudjelal, Farida, Lebrihi, Ahmed, Mathieu, Florence, Sabaou, Nasserdine, Zitouni, Abdelghani   +4 more
core   +3 more sources

Interactive effects of vinclozolin and testosterone propionate on pregnancy and sexual differentiation of the male and female SD rat.

Toxicological Sciences, 2004
In mammals, androgens are essential in directing mammalian sexual differentiation of the male phenotype. Administration of testosterone during this period alters female development in a male-like direction, whereas exposure to an androgen receptor ...
C. Wolf, G. LeBlanc, L. Gray
semanticscholar   +1 more source

Gamma Irradiated Rhodiola sachalinensis Extract Ameliorates Testosterone-Induced Benign Prostatic Hyperplasia by Downregulating 5-Alpha Reductase and Restoring Testosterone in Rats

Molecules, 2019
The effect of Rhodiola sachalinensis Boriss extract irradiated with 50 kGy gamma rays (HKC) on benign prostatic hyperplasia (BPH) was investigated. Seven-week-old male SD rats received a subcutaneous injection of 20 mg/kg of testosterone propionate (TP ...
Qi Xin, Mi-Jin Kwon, Ju-Woon Lee, Kwan-Soo Kim, Hao Chen, Maria G. Campos, Rosa Tundis, Cheng-Bi Cui, Young Ho Cho, Hui Cao   +9 more
doaj   +1 more source

Testosterone aggravates cerebral vascular injury by reducing plasma HDL levels

Open Life Sciences, 2020
Testosterone is often used to improve the physiological function. But increased testosterone levels affect blood lipids and cause inflammation and oxidative stress, which are risk factors for vascular diseases.
Jin Tao, Wang Lu, Li Dongbo, Yang Tao, Zhou Yuefei   +4 more
doaj   +1 more source

Supraphysiological Levels of Testosterone Induce Vascular Dysfunction via Activation of the NLRP3 Inflammasome

Frontiers in Immunology, 2020
Background: Both supraphysiological and subphysiological testosterone levels are associated with increased cardiovascular risk. Testosterone consumption at supraphysiological doses has been linked to increased blood pressure, left ventricular hypertrophy,
Juliano Vilela Alves, Rafael Menezes da Costa, Rafael Menezes da Costa, Camila André Pereira, Aline Garcia Fedoce, Carlos Alberto Aguiar Silva, Fernando Silva Carneiro, Núbia Souza Lobato, Rita C. Tostes   +8 more
doaj   +1 more source

Effect of Testosterone Propionate in Eunuchoidism

Experimental Biology and Medicine, 1938
ConclusionTestosterone propionate causes enlargement of the prostate and progression of secondary sex characters in the eunuchoid, together with a gain in weight, nitrogen and sodium retention, and a slight increase in the basal metabolic rate.
Fred C. Koch, Kathryn Knowlton, Irene Sandiford, Allan T. Kenyon, A. Hughes Bryan   +4 more
openaire   +2 more sources

Microbiological Foundations to Optimise Intrinsic Capacity and Promote Healthy Ageing: An Integration Into the Life Course Approach

Aging Cell, EarlyView.
Gut microbiota composition may influence trajectories of intrinsic capacity throughout life. Factors that positively or negatively impact gut microbiota (determining eubiosis or dysbiosis, respectively) can affect health, potentially acting through short‐chain fatty acids and their metabolic and anti‐inflammatory functions.
Christoph Benner, Matteo Cesari, Ritu Sadana   +2 more
wiley   +1 more source

Effect of Testosterone Propionate on Greatinuria.

Experimental Biology and Medicine, 1939
Numerous reports have been presented concerning the effects of castration, administration of androgens and estrogens in pure form, implantation of gonads, and injections of gonad extracts or saline suspensions upon creatine and creatinine metabolism in the normal and castrate animal.
J. R. Coffman, F. C. Koch
openaire   +2 more sources

Single‐Cell Sequencing Reveals That CD4+ T Cells Eliminate Senescent Prostate Epithelium to Delay Progression of Benign Prostatic Hyperplasia

Aging Cell, EarlyView.
Senescent BPH epithelial cells secrete CXCL13 to recruit CD4+ T cells via CXCR5. Cytotoxic CD4+ T cells eliminate senescent cells through MHC‐II–dependent recognition. Tregs suppress, while B cells show minimal effect. This immune axis modulates senescent cell clearance and may influence BPH progression.
Zheng Li, Xiaofei Wang, Zhifu Liu, Senmao Li, Zhenan Zhang, Chenchen Huang, Yixiao Liu, Xingxing Tang, Jiaen Zhang, Peimin Zhou, Ying Gan, Yu Fan, Yisen Meng, Kaiwei Yang, Shuai Hu, Qian Zhang, Wei Yu   +16 more
wiley   +1 more source