Results 161 to 170 of about 24,909,033 (334)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Chamber-by-Chamber Measurements of Planktonic Foraminiferal Mg, Sr, and Na to Ca Ratios With Femtosecond LA-ICP-MS. [PDF]

Rapid Commun Mass Spectrom
Yoshimura T, Chang Q, Ohkouchi N, Ishitani Y, Ulanova D, Endo H, Kuroda J, Ujiié Y.   +7 more
europepmc   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

"Universal health coverage and priority diseases diagnostics: a case study of Essential Package of Health Services from Pakistan". [PDF]

Lancet Reg Health Southeast Asia
Zeeshan M, Shakoor S, Siddiqui AR, Hasan R.   +3 more
europepmc   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Selecting measures of visual function to classify diabetic retinopathy status: a cross-sectional study. [PDF]

BMJ Open Ophthalmol
Wright DM, Chakravarthy U, Das R, Graham KW, Naskas TT, Peto T, Hogg RE.   +6 more
europepmc   +1 more source

A Comparative Study of Unit Root Tests with Panel Data and a New Simple Test

, 1999
G. Maddala, Shaowen Wu
semanticscholar   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Efficient Tests for an Autoregressive Unit Root

, 1992
G. Elliott, T. Rothenberg, J. Stock
semanticscholar   +1 more source

Nonparametric permutation tests for functional neuroimaging: A primer with examples

Human Brain Mapping, 2002
Thomas E. Nichols, A. Holmes
semanticscholar   +1 more source