Results 61 to 70 of about 58,219 (300)

Barotropic equations of state in 4D Einstein-Maxwell-Gauss-Bonnet stellar distributions

Nuclear Physics B
We investigate the role of a linear barotropic equation of state (p=γρ) on the structure of charged stars under higher curvature effects induced by the Gauss-Bonnet invariants in 4 dimensions.
Sudan Hansraj, Siyamthanda Remember Mngadi, Abdelghani Errehymy   +2 more
doaj   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Graviton Physics: A Concise Tutorial on the Quantum Field Theory of Gravitons, Graviton Noise, and Gravitational Decoherence

Universe
The detection of gravitational waves in 2015 ushered in a new era of gravitational wave (GW) astronomy capable of probing the strong field dynamics of black holes and neutron stars.
Jen-Tsung Hsiang, Hing-Tong Cho, Bei-Lok Hu   +2 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Relativity in the Global Positioning System

Living Reviews in Relativity, 2003
The Global Positioning System (GPS) uses accurate, stable atomic clocks in satellites and on the ground to provide world-wide position and time determination.
Ashby Neil
doaj  

Towards a loophole-free test of Bell's inequality with entangled pairs of neutral atoms

, 2009
Experimental tests of Bell's inequality allow to distinguish quantum mechanics from local hidden variable theories. Such tests are performed by measuring correlations of two entangled particles (e.g. polarization of photons or spins of atoms).
Cabello, Adan, Henkel, Florian, Krug, Michael, Rosenfeld, Wenjamin, Volz, Juergen, Weber, Markus, Weinfurter, Harald, Zukowski, Marek   +7 more
core   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Fundamental constants and their variability in theories of High Energy Physics

, 2008
The Standard Model of particle physics and the theory of General Relativity (GR) currently provide a good description of almost all phenomena of particle physics and gravitation that have received controlled experimental tests.
Dent, Thomas
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Student experiences of virtual reality - a case study in learning special relativity

, 2009
We present a study of student learning through the use of virtual reality. A software package is used to introduce concepts of special relativity to students in a game-like environment where users experience the effects of travelling at near light speeds.
Craig Savage, Dominic McGrath, Gamow G., Margaret Wegener, McGrath D., Mermin N. D., Michael Williamson, Timothy J. McIntyre   +7 more
core   +1 more source