Results 81 to 90 of about 66,973 (276)

Total Synthesis of Annonaceous Acetogenins Belonging to the Non-Adjacent Bis-THF and Non-Adjacent THF-THP Sub-Classes

Molecules, 2010
The synthesis of the subgroups of acetogenins containing non-adjacent bis-THF and non-adjacent THF-THP core units is reviewed. Specifically, total syntheses of gigantecin, 4-deoxygigantecin, cis-sylvaticin, squamostatin-C, squamostatin-D, sylvaticin and ...
Richard C. D. Brown, Ian B. Spurr
doaj   +1 more source

Machine Learning for Green Solvents: Assessment, Selection and Substitution

Advanced Science, EarlyView.
Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta, Janhavi Nistane, Abhishek Sose, Harikrishna Sahu, Rampi Ramprasad   +4 more
wiley   +1 more source

Experimental and theoretical cross sections for positron collisions with 3-hydroxy-tetrahydrofuran

, 2013
Cross section results from a joint experimental and theoretical investigation into positron scattering from 3-hydroxy-tetrahydrofuran (3H-THF) are presented.
Francisco Blanco (717849), R P McEachran (20231214), James P Sullivan (20231199), M J Brunger (20231220), Luca Chiari (5158802), Prasanga Palihawadana (20231205), Gustavo Garcia (3706033), Casten Makochekanwa (20231211), J R Machacek (20231208), Stephen J Buckman (20231217)   +9 more
core   +1 more source

Pore multi-fractal characteristics of coal under true triaxial tetrahydrofuran hydraulic injection

Meitan xuebao
The efficiency of coalbed methane extraction is closely related with multifractal characteristics of pore structures. Clarifying the mechanism of changes in pore structure in coal affected by hydraulic injection has theoretical significance for the ...
Sheng XUE, Feilin HAN, Chunshan ZHENG, Shuaili LIU, Bingjun LIU   +4 more
doaj   +1 more source

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

Advanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao, Maryam Hatami, Sumeyye Koc, Qing Jiang, Thomas Skutella, Yuanfeng Zhang   +5 more
wiley   +1 more source

Dual‐Module Near‐Infrared Fluorophores Discovery System via Knowledge Transfer

Advanced Science, EarlyView.
This study presents a dual‐module deep learning system for the design of near‐infrared (NIR) fluorophores. A large molecular library is generated and analyzed, leading to the suggestions of promising candidates. The effectiveness of the system is further validated through the synthesis, characterization, and in vivo imaging, demonstrating its potential
Yixin Zhu, Xia Ling, Xianhe Zhang, Chuanjiang Jian, Leilei Shi, Wentao Song, Xiaonan Wang, Bin Liu   +7 more
wiley   +1 more source

Extraction of beta-carotene from the microalga Dunaliella salina using bacterial lipase enzyme and organic solvent under varying stress conditions

Frontiers in Marine Science
Nowadays there is a growing trend towards carotenoids obtained from natural sources such as microalgae. Dunaliella salina is among the most significant natural sources of beta-carotene for commercial scale, which is used in many food industries ...
Fotoon Sayegh, Fotoon Sayegh, Mona J. Al-naghrani, Mona J. Al-naghrani, Ramzi H. Amran, Ramzi H. Amran, Mamdoh T. Jamal, Nada M. Nass, Nada M. Nass, Wessam F. Felemban, Wessam F. Felemban, Samyah D. Jastaniah, Sathianeson Satheesh   +12 more
doaj   +1 more source

Isolation of a Bis-Iodurated Tetra-THF as a Trace Product from the Oxidation of Squalene with RuO4 and Its Double Ring Expansion to a Novel bis-THF-bis-THP Compound

Molecules, 2011
A novel bis-iodurated polyether compound, based on an unprecedented tetra-THF backbone, has been isolated as a trace by-product of the oxidation of squalene with the catalytic system RuO2(cat.)/NaIO4.
Nicola Borbone, Giorgia Oliviero, Roberto Centore, Angela Tuzi, Sabrina Zaccaria, Vincenzo Piccialli   +5 more
doaj   +1 more source

Ultrasound‐Recharged Sub‐Nanometer Palladium Catalysts for on‐Demand and Self‐Terminating Bioorthogonal Prodrug Activation in Cancer Therapy

Advanced Science, EarlyView.
Safe and precise bioorthogonal therapy of tumors was achieved by an ultrasound‐responsive heterostructured nanoreactor with on‐demand catalytic activity. Under piezoelectric catalysis, the system undergoes reversible Pd2+/Pd0 redox cycling, concurrently enabling spatiotemporally controlled prodrug activation and self‐terminating catalytic dose ...
Daqing Xia, Lei Liu, Shuang Jin, Guangxu Fang, Chang Yu, Yunyun Wu, Lunli Xiang, Hongrui Zhu, Zhenqiang Wang, Jixi Zhang   +9 more
wiley   +1 more source

Hydrosulfonylation Reaction with Arenesulfonyl Chlorides and Tetrahydrofuran: Conversion of Terminal Alkynes into Cyclopentylmethyl Sulfones [PDF]

, 2017
International audienceAn efficient and simple radical chain reaction to convert terminal alkynes into arenesulfonylmethylcyclopentanes is described. The reaction involves a radical addition-translocation-cyclization process and necessitates solely the ...
Gloor, Christian Simon, Christian Simon Gloor, Fabrice Dénès, Denes, Fabrice, Renaud, Philippe, Philippe Renaud   +5 more
core   +2 more sources