Living unicellular eukaryote Tetrahymena pyriformis as a model for study of mitochondrial energetics in mammalian cells under conditions of reduced oxidative metabolism. [PDF]
, 2010 Some “animal-like” protozoa are used instead of mammalian cells in diverse investigations. _Tetrahymena pyriformis_ cells in stationary phase of growth and washed from oxidative substrates (_T.pyriformis_) function under conditions of ...
Elena Mokhova
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Activity of 6-aryl-pyrrolo[2,3-d]pyrimidine-4-amines to Tetrahymena [PDF]
, 2012 A series 6-aryl-pyrrolo[2,3-d]pyrimidine-4-amines (43 compounds), some of which are epidermal growth 22 factor tyrosine kinase inhibitors, were tested for their protozoal toxicity using an environmental Tetrahy- 23 mena strain as model organism.
Charnock, Colin +3 more
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Miniaturization and application of the MTT assay to evaluate metabolic activity of protozoa in the presence of toxicants [PDF]
, 1999 This paper describes a critical evaluation of a miniaturised colorimetric assay, using MTT (3-[4,5- dimethyl-thiazol-2-yl]-2,5-diphenyl-tetrazolium bromide) reduction, applied to protozoan viability testing. The toxic substances used were copper, zinc,
Carvalho, Graça Simões de +4 more
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Understanding the errors of SHAPE-directed RNA structure modeling [PDF]
, 2011 Single-nucleotide-resolution chemical mapping for structured RNA is being rapidly advanced by new chemistries, faster readouts, and coupling to computational algorithms. Recent tests have shown that selective 2'-hydroxyl acylation by primer extension (SHAPE) can give near-zero error rates (0-2%) in modeling the helices of RNA secondary structure. Here,
arxiv +1 more source
Оценка биологической ценности и безвредности пищевых продуктов с целью разработки рационов для туристско-оздоровительной деятельности [PDF]
, 2016 Качественный состав пищи для людей, ведущий активный образ жизни, должен подбираться с учетом индивидуальных физических характеристик, уровня нагрузок. Но в любом случае пища должна содержать все необходимые макрои микроэлементы.
Бондарук, Алла Михайловна +4 more
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Effect of different toxic compounds on ATP content and acid phosphatase activity in axenic cultures of Tetrahymena pyriformis [PDF]
, 2004 The sensitivity of protozoa, and particularly ciliated protozoa, to environmental changes suggested a study on the physiological responses arising from exposure to toxic compounds.
Akers +30 more
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Machine learning for the prediction of phenols cytotoxicity
IJAIN (International Journal of Advances in Intelligent Informatics), 2022 Quantitative structure-activity relationships (QSAR) are relevant techniques that assist biologists and chemists in accelerating the drug design process and help understanding many biological and chemical mechanisms.
Latifa Douali
doaj +1 more source
Germ Line-Specific DNA Sequences are Present on All Five Micronuclear Chromosomes in \u3cem\u3eTetrahymena thermophila\u3c/em\u3e [PDF]
, 1983 The development of the macronucleus from the zygotic micronucleus in the ciliated protozoan Tetrahymena spp. involves the elimination of specific DNA sequences (M. C. Yao and M. Gorovsky, Chromosoma 48:1-18 1974).
Karrer, Kathleen M.
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A comparative study using a fluorescence-based and a direct-count assay to determine cytotoxicity in Tetrahymena pyriformis [PDF]
, 2002 A novel cellular cytotoxicity assay using two fluorescent dyes was developed as an alternative method to the standard direct count of viable protozoa under light microscopy.
Bogaerts +28 more
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Wall Drag on Free-Moving Ciliated Micro-Organisms [PDF]
, 1973 It is generally assumed that wall drag on free-moving, self-propelled or passively moving micro-organisms is not significant under normal observation conditions. Yet the point at which such drag becomes significant has not been determined quantitatively.
Winet, H.
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