Results 61 to 70 of about 7,672 (207)

Fusion Pores as Regulators of Quantal Size and Cellular Physiology

open access: yesBioEssays, Volume 47, Issue 11, November 2025.
During regulated exocytosis, membrane fusion regulatory factors act directly on SNAREs and membrane lipids to control fusion pore dynamics. This, in turn, leads to a differential amount of cargo release (referred to in this article as “quantal size”) across various cell types, thereby triggering distinct physiological cues.
Bhavya R. Bhaskar   +3 more
wiley   +1 more source

Nucleus-specific linker histones Hho1 and Mlh1 form distinct protein interactions during growth, starvation and development in Tetrahymena thermophila [PDF]

open access: yes, 2019
Chromatin organization influences most aspects of gene expression regulation. The linker histone H1, along with the core histones, is a key component of eukaryotic chromatin.
Pearlman, Ronald E.   +7 more
core   +1 more source

Evaluation of phenylethylamine type entactogens and their metabolites relevant to ecotoxicology – a QSAR study

open access: yesActa Pharmaceutica, 2019
The impact of the selected entactogens and their o-quinone metabolites on the environment was explored in QSAR studies by the use of predicted molecular descriptors, ADMET properties and environmental toxicity parameters, i.e., acute toxicity in ...
Takač Milena Jadrijević-Mladar   +2 more
doaj   +1 more source

Tandemly repeated C-C-C-C-A-A hexanucleotide of Tetrahymena rDNA is present elsewhere in the genome and may be related to the alteration of the somatic genome. [PDF]

open access: yes, 1981
The ribosomal RNA genes of the Tetrahymena macronucleus exist as extrachromosomal, linear molecules. The termini of these molecules have been shown to contain the tandemly repeated hexanucleotide (C-C-C-C-A-A)n.
Blackburn, E, Gall, J, Yao, MC
core  

UPLC‐ESI‐QTOF‐MS/MS Profiling, Antioxidant, and Cytotoxicity Potentials of Marrubium vulgare L. Extracts: Experimental Analysis and Computational Validation

open access: yesChemistry &Biodiversity, Volume 22, Issue 10, October 2025.
ABSTRACT Plant extracts are emerging as valuable options for food additives and therapeutic treatments. This study evaluated the phytochemical profile, antioxidant activity, and cytotoxicity of aerial parts of Marrubium vulgare L. crude extract (MVCE) and its subfractions.
Ines El Mannoubi   +8 more
wiley   +1 more source

Influence of cellular shape on sliding behavior of ciliates

open access: yesCommunicative & Integrative Biology, 2018
Some types of ciliates accumulate on solid/fluid interfaces. This behavior is advantageous to survival in nature due to the presence of sufficient nutrition and stable environments.
Yukinori Nishigami   +6 more
doaj   +1 more source

New sensitive assay for phosphatidylserine decarboxylase based on the detection of CO2 from nonradiolabeled phosphatidylserine

open access: yesJournal of Lipid Research, 1973
A new rapid assay for phosphatidylserine decarboxylase, which is sensitive in the nanomolar range, is described. Synthesis of radiolabeled phosphatidylserine for use as a substrate is not required, since the assay, unlike previous ones, is based on the ...
Thomas G. Warner, Edward A. Dennis
doaj   +1 more source

Machine learning for the prediction of phenols cytotoxicity

open access: yesIJAIN (International Journal of Advances in Intelligent Informatics), 2022
Quantitative structure-activity relationships (QSAR) are relevant techniques that assist biologists and chemists in accelerating the drug design process and help understanding many biological and chemical mechanisms.
Latifa Douali
doaj   +1 more source

Probing the Inhibitory Potential of Halogenated Symmetrical Formamidine Against MAO‐A and MAO‐B: Structural Elucidation, Molecular Dynamic Simulation and DFT Computational Studies

open access: yesChemistry &Biodiversity, Volume 22, Issue 10, October 2025.
ABSTRACT A halogenated symmetrical formamidine, N,N′‐bis(3‐chloro‐4‐fluorophenyl)formamidine (FCF) was synthesized by the condensation reaction between triethyl orthoformate and 3‐chloro‐4‐fluoroaniline in 1:2 ratio. The compound FCF was characterized by FT‐IR, mass, NMR (1H and 13C) spectroscopic techniques and the purity was confirmed by elemental ...
Segun D. Oladipo   +6 more
wiley   +1 more source

Assessment of biological value and safety of food in the diet developing for tourism and recreational activities [PDF]

open access: yes, 2016
The qualitative composition of food for people leading an active life, should be selected based on individual physical characteristics. Anyway, the food must contain all the essential macro and micro el-ements.
Bondaruk, A. M.   +4 more
core  

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