Results 51 to 60 of about 972 (122)

The Negative Impact of a Non‐Therapeutic Laparotomy in Patients With Inoperable Colorectal Peritoneal Metastases

Journal of Surgical Oncology, Volume 133, Issue 7, Page 843-851, June 2026.
ABSTRACT Background The peritoneum is the third most prevalent location for metastases of colorectal cancer. In patients with resectable disease, cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (CRS‐HIPEC) is the preferred treatment in the Netherlands, achieving median overall survival (OS) of 36–42 months. However, during
Teun van den Heuvel, Lars van Kesteren, Simon Nienhuijs, Pim Burger, Tineke Buffart, Jurriaan Tuynman, Ignace De Hingh   +6 more
wiley   +1 more source

Simulation Framework to Investigate Efficacy and Ocular Safety of Belantamab Mafodotin Combinations in Relapsed/Refractory Multiple Myeloma

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 6, June 2026.
ABSTRACT Quantitative modeling can guide drug development and regulatory decisions by providing insights into pharmacokinetics, pharmacodynamics, efficacy, and safety. Integrating models allows simulations that support dosing considerations. A simulation framework for belantamab mafodotin (B) in relapsed/refractory multiple myeloma was developed using ...
Fernando Carreño, Martijn van Noort, Adekemi Taylor, Stefan Zeiser, Theodoros Papathanasiou, Teun M. Post, Yi Ting (Kayla) Lien, Yu Liu Ho, Geraldine Ferron‐Brady   +8 more
wiley   +1 more source

The Use of Aristotle’s Biology in Nemesius’ On Human Nature

Revista de Filosofia Antiga, 2021
Towards the end of the fourth century CE Nemesius, bishop of Emesa in Syria, composed his treatise On Human Nature (Περὶ φύσεως ἀνθρώπου). The nature of the soul and its relation to the body are central to Nemesius’ treatment. In developing his argument,
Teun Tieleman
doaj  

meta‐Methylation of Aniline and Anisole Derivatives via Palladium/S, O‐Ligand/Norbornene Cooperative Catalysis

ChemistryEurope, Volume 4, Issue 5, May 2026.
The introduction of methyl groups into lead compounds is a common strategy in medicinal chemistry to improve their pharmaceutical properties. However, methylation protocols avoiding prefunctionalized substrates or directing groups are rare. Herein, we disclose a selective meta‐CH methylation of anilines and anisole derivatives that eliminates the need
Florian Papp, Verena Sukowski, Jos Verboom, Magnus J. Johansson, M. Ángeles Fernández‐Ibáñez   +4 more
wiley   +1 more source

Reliability and Radiographic Correlation of the Foot Posture Index-6: A Multi-Rater Analysis in Symptomatic and Asymptomatic Individuals

Diagnostics
Background/Objectives: The foot posture index (FPI-6) is a practical clinical tool for evaluating standing foot posture using six specific criteria. Although widely used, its reliability and correlation with radiographic parameters remain uncertain. This
Min Gyu Kyung, Yun Jae Cho, Jae Hee Lee, Min Seok Shin, Jay Hoon Park, Dong Yeon Lee   +5 more
doaj   +1 more source

Sharing the light, impact of solar parks on plant productivity, soil microbes and soil organic matter

PLANTS, PEOPLE, PLANET, Volume 8, Issue 3, Page 1000-1013, May 2026.
Solar parks enable renewable energy production at a large scale, thereby reducing greenhouse gas emissions. However, the effects of this change in land use on vegetation and soil health are still largely unknown. In this study, we determined the impacts of solar parks on vegetation, soil biota and soil carbon between and below solar panels.
Luuk Scholten, Ron G. M. de Goede, Anna Edlinger, Bas B. Van Aken, Gerlinde B. De Deyn   +4 more
wiley   +1 more source

Lower Dose‐Normalized Tacrolimus Exposure in CYP3A5*6 vs. *3 Loss‐of‐Function Allele Carriers: A Longitudinal Retrospective Real‐World Study in Kidney Transplant Recipients

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 942-952, April 2026.
Pharmacogenomic research has historically focused on individuals of European ancestry, leading to the underrepresentation of genetic variants common in non‐European populations. This bias is exemplified by CYP3A5*6, a functionally consequential variant common in individuals of African ancestry (MAF: 11–19%) but virtually absent in Europeans (MAF: 0.15%)
Amar D. Levens, Dirk Jan A. R. Moes, Yanick Boer, Aiko P. J. de Vries, Dorottya K. de Vries, Danny van der Helm, Soufian Meziyerh, Dave L. Roelen, Stefan Böhringer, Teun Van Gelder, Jesse J. Swen   +10 more
wiley   +1 more source

The Art of Life: An Ancient Idea and Its Survival [PDF]

SCHOLE, 2008
Teun Tieleman (UCLA / Utrecht University) surveys the history of the philosophical notion of the ‘art of life’, starting from its originator Socrates and his ancient successors down to its role among present-day philosophers. Apart from Socrates, special
Tieleman, Teun
doaj  

The Art of Ramon Llull (1232–1350): From Theology to Mathematics

Studies in Logic, Grammar and Rhetoric, 2016
In the present paper the roots of the Art of the Catalan philosopher Ramon Llull are examined. Moreover the impact of the Art on seventeenth mathematics is briefly discussed.
Koetsier Teun
doaj   +1 more source

Single‐Molecule Imaging and Spectroscopy Enables Quantification of Location‐Dependent Light–Matter Interactions on Nanoantennas

Small Science, Volume 6, Issue 3, March 2026.
The fluorescence intensity as well as the spectral shape of the emission of single dye molecules strongly depend on the molecules’ exact position relative to plasmonic nanoparticles in hybrid systems. By point‐spread function modification analysis, the vertical binding location of single fluorophores on gold nanocones is obtained and correlated to both
Lukas Lang, Sjoerd Nooteboom, Teun A. P. M. Huijben, Sarojini Mahajan, Rodolphe Marie, Peter Zijlstra, Monika Fleischer   +6 more
wiley   +1 more source