Results 21 to 30 of about 10,446 (210)

Diálogo con Teun van Dijk: discurso, poder e ideología

open access: yesÍconos, 1998
Necesitamos investigaciones críticas más prácticas sobre problemas sociales reales como el racismo y otras formas de desigualdad.
Sebastián Mantilla Baca
doaj   +4 more sources

RRAGD p.(Ser76Leu) Variant Causes Dysregulated Expression of Muscle Development and Cytoskeleton Genes in Cardiomyocytes. [PDF]

open access: yesFASEB J
Under normal conditions, RagD and mTORC1 respond to amino acid changes. Upon stimulation, active mTORC1 phosphorylates S6K, 4E‐BP1, and TFEB. In response to starvation, mTORC1 is inactive. Our data indicate that the RRAGD p.(Ser76Leu) variant maintains the phosphorylation of mTORC1 targets during starvation in T‐REx HeLa cells.
Adella A   +11 more
europepmc   +2 more sources

Simulation Framework to Investigate Efficacy and Ocular Safety of Belantamab Mafodotin Combinations in Relapsed/Refractory Multiple Myeloma. [PDF]

open access: yesCPT Pharmacometrics Syst Pharmacol
ABSTRACT Quantitative modeling can guide drug development and regulatory decisions by providing insights into pharmacokinetics, pharmacodynamics, efficacy, and safety. Integrating models allows simulations that support dosing considerations. A simulation framework for belantamab mafodotin (B) in relapsed/refractory multiple myeloma was developed using ...
Carreño F   +8 more
europepmc   +2 more sources

Single-Molecule Imaging and Spectroscopy Enables Quantification of Location-Dependent Light-Matter Interactions on Nanoantennas. [PDF]

open access: yesSmall Sci
The fluorescence intensity as well as the spectral shape of the emission of single dye molecules strongly depend on the molecules’ exact position relative to plasmonic nanoparticles in hybrid systems. By point‐spread function modification analysis, the vertical binding location of single fluorophores on gold nanocones is obtained and correlated to both
Lang L   +6 more
europepmc   +2 more sources

Inside-Out Approach of Lumbar Endoscopic Unilateral Laminotomy for Bilateral Decompression: A Detailed Technical Description, Rationale and Outcomes [PDF]

open access: yesNeurospine, 2020
Although lumbar stenosis was recognized as a contraindication for endoscopic spine surgery in the past, the advancement in endoscopic system design and development of approach techniques and strategies now enabled the endoscopic spine surgeons to manage ...
Kang Taek Lim   +2 more
doaj   +1 more source

Similar Individual Serum Levels of MCP-1, TNF-α, and IL-6 From Periodontitis Patients Before and 1 Year After Treatment. [PDF]

open access: yesScand J Immunol
Periodontitis patients before and 1 year present with similar levels of MCP‐1, TNF‐α, and IL‐6, cytokine equilibrium. MCP‐1, TNF‐α, and IL‐6 are not correlated per individual, meaning that some individuals may present with relatively high levels of one of the cytokines with lower levels of the other cytokines or cytokine signature.
de Vries TJ   +5 more
europepmc   +2 more sources

Percutaneous Stenoscopic Lumbar Decompression with Paramedian Approach for Foraminal/Extraforaminal Lesions [PDF]

open access: yesAsian Spine Journal, 2019
The lumbar foramen is affected by different degenerative diseases, including extraforaminal disc herniation, foraminal stenosis (FS), and degenerative or spondylolytic spondylolisthesis.
Han Ga Wi Nam   +4 more
doaj   +1 more source

Therapeutic Feasibility of Full Endoscopic Decompression in One- to Three-Level Lumbar Canal Stenosis via a Single Skin Port Using a New Endoscopic System, Percutaneous Stenoscopic Lumbar Decompression [PDF]

open access: yesAsian Spine Journal, 2019
Study Design This retrospective study involved 450 consecutive cases of degenerative lumbar stenosis treated with percutaneous stenoscopic lumbar decompression (PSLD).
Kang Taek Lim   +5 more
doaj   +1 more source

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