Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
A critical discussion of the concept of 'performance literature' as applied to the cross-cultural and comparative analysis of literature, with special but not exclusive reference to the literatures of Asia and ...
Finnegan, Ruth
core +5 more sources
Federico García Lorca’s ‘impossible’ theatre staged [PDF]
This study explores the relatively unknown area of Federico García Lorca’s theatre work which he himself termed ‘impossible’ and ‘unperformable’. With the director’s task of preproduction research in mind, the study examines biographical research as well
Tyler, Daniel James
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The sweetheart factor: Tracing translation in Martin Crimp’s writing for theatre [PDF]
Martin Crimp’s activity as a playwright includes the translation and adaptation of the theatrical works of other writers. This article considers how Crimp’s theoretical and practical engagement with translation is manifested in his writing for the stage.
Brodie, G
core +1 more source
Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort
ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen +11 more
wiley +1 more source
Improvisation in the arts of the middle ages and renaissance [PDF]
not ...
Katritzky, M. A.
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Enhanced Magnetic Trap Loading for Atomic Strontium
We report on a technique to improve the continuous loading of atomic strontium into a magnetic trap from a Magneto-Optical Trap (MOT). This is achieved by adding a depumping laser tuned to the 3P1 to 3S1 (688-nm) transition. The depumping laser increases
Barker, D. S. +3 more
core +1 more source
WRITING UTOPIA NOW: Utopian Poetics In The Work Of Theresa Hak Kyung Cha [PDF]
This thesis examines Theresa Hak Kyung Cha’s DICTEE (1982), Audience Distant Relative (1977) and Reveillé dans la Brume (Awakened in the Mist) (1977). The premise of the thesis is an exploration of the various ways in which these works both perform and ...
Willow, S., Willow, S.
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Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund +3 more
wiley +1 more source
IMPACT: The Journal of the Center for Interdisciplinary Teaching and Learning. Volume 5, Issue 1, Winter 2016 [PDF]
Impact: The Journal of the Center for Interdisciplinary Teaching & Learning is a peer-reviewed, biannual online journal that publishes scholarly and creative non-fiction essays about the theory, practice and assessment of interdisciplinary education ...
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