Results 91 to 100 of about 23,124,591 (291)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Emotional Text-To-Speech in Japanese Using Artificially Augmented Dataset

IEEE Access
This study explores the feasibility of using artificial emotional speech datasets generated by existing artificial voice-generating software as an alternative to human-generated datasets for emotional speech synthesis.
Mujahid Jamal A. Khalifah, Michal Ptaszynski, Fumito Masui   +2 more
doaj   +1 more source

Gender and leadership in Judith: A Greimassian contribution

HTS Teologiese Studies/Theological Studies, 2018
The structuring of the narrative with characters assigned to fulfil particular roles is often indicative of an author’s possible intent. Thus, characterisation, in a story, is not neutral about its rhetorical intent; it generally reveals cultural values ...
Risimati S. Hobyane, Dickh M. Kanonge, Pierre Jordaan   +2 more
doaj   +1 more source

Americans and Text Messaging [PDF]

, 2011
Presents survey findings about the use of text messaging, including average numbers of text messages and voice calls per day by gender, age, race/ethnicity, income, and education level.
Aaron Smith
core  

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

On German verb sense disambiguation: A three-part approach based on linking a sense inventory (GermaNet) to a corpus through annotation (TGVCorp) and using the corpus to train a VSD classifier (TTvSense)

Journal of Language Modelling
We develop a three-part approach to Verb Sense Disambiguation (VSD) in German. After considering a set of lexical resources and corpora, we arrive at a statistically motivated selection of a subset of verbs and their senses from GermaNet.
Dominik Mattern, Wahed Hemati, Andy Lücking, Alexander Mehler   +3 more
doaj   +2 more sources

Die tema van God se spraak in Hebreërs se inleidingsformules

In die Skriflig, 2015
Alhoewel die voorkoms en gebruik van die Ou Testament in die meeste navorsing oor Hebreërs besonder baie aandag geniet, is dit nie die geval met die Hebreërskrywer se gebruik van inleidingsformules vir sy Ou-Testamentiese aanhalings nie.
Albert J. Coetsee, Gert J.C. Jordaan
doaj   +1 more source