Results 81 to 90 of about 2,419,982 (257)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Towards Automated Classification of Adult Attachment Interviews in German Language Using the BERT Language Model

open access: yesIEEE Access
Attachment theory, pioneered by John Bowlby, has become a prominent psychological framework that aids in our comprehension of human behavior within close relationships.
Teodor Stoev   +5 more
doaj   +1 more source

stm: An R Package for Structural Topic Models

open access: yesJournal of Statistical Software, 2019
This paper demonstrates how to use the R package stm for structural topic modeling. The structural topic model allows researchers to flexibly estimate a topic model that includes document-level metadata.
Margaret E. Roberts   +2 more
doaj   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

The Role of Digital Tools in Historical Research: A Study on the Intellectual Network of Gerbert of Aurillac

open access: yesOrtaçağ Araştırmaları Dergisi
This study employs digital tools to visualize the intellectual network of Pope Sylvester II (Gerbert of Aurillac) and to compare it with established historical narratives.
Bedia Göktepe   +1 more
doaj   +1 more source

Machine Learning Blunts the Needle of Advanced SQL Injections

open access: yesMendel, 2019
SQL injection is one of the most popular and serious information security threats. By exploiting database vulnerabilities, attackers may get access to sensitive data or enable compromised computers to conduct further network attacks.
Marina Volkova   +2 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Study on the Evolution Mechanism of Cultural Landscapes Based on the Analysis of Historical Events—A Case Study of Gubeikou, Beijing

open access: yesBuildings
The cultural landscape of Gubeikou, with distinct historical stratification and event-relatedness, bears unique value. Against the backdrop of increasingly prominent themes of cultural heritage development and transformation, research on Gubeikou’s ...
Ding He   +3 more
doaj   +1 more source

Synthetically generated text for supervised text analysis

open access: yesPolitical Analysis
AbstractLarge language models are a powerful tool for conducting text analysis in political science, but using them to annotate text has several drawbacks, including high cost, limited reproducibility, and poor explainability. Traditional supervised text classifiers are fast and reproducible, but require expensive hand annotation, which is especially ...
openaire   +2 more sources

Learning Concept Hierarchies from Text Corpora using Formal Concept Analysis

open access: yes, 2004
Cimiano P, Hotho A, Staab S. Learning Concept Hierarchies from Text Corpora using Formal Concept Analysis. Karlsruhe: Universität Karlsruhe, Institut für Angewandte Informatik und Formale Beschreibungsverfahren (AIFB ...
Staab, Steffen   +2 more
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