Results 51 to 60 of about 41,163,437 (285)

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Modelling Discourse-related terminology in OntoLingAnnot’s ontologies [PDF]

open access: yes, 2010
Recently, computational linguists have shown great interest in discourse annotation in an attempt to capture the internal relations in texts. With this aim, we have formalized the linguistic knowledge associated to discourse into different linguistic ...
Aguado de Cea, G., Pareja-Lora, A.
core  

Chinese Scientific Literature Annotation Method Based on Large Language Model [PDF]

open access: yesJisuanji gongcheng
High-quality annotated data are crucial for Natural Language Processing(NLP) tasks in the field of Chinese scientific literature. A method of annotation based on a Large Language Model(LLM) was proposed to address the lack of high-quality annotated ...
YANG Dongju, HUANG Juntao
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Maia: an Open Collaborative Platform for Text Annotation, E-Lexicography, and Lexical Linking

open access: yesUmanistica Digitale
Although open tools for manual text annotation and the creation of lexical resources have been available for some years, there is currently no integrated tool that allows, within the same environment, annotating a text corpus, building a computational ...
Emiliano Giovannetti   +5 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Text-based Semantic Annotation Service for Multimedia Content in the Esperonto project [PDF]

open access: yes, 2004
Within the Esperonto project, an integration of NLP, ontologies and other knowledge bases, is being performed with the goal to implement a semantic annotation service that upgrades the actual Web towards the emerging Semantic Web.
Corcho, Oscar   +3 more
core  

Methods, Challenges, and Future Directions in Annotation and Indexing of Classical Chinese Medical Texts: A Narrative Review

open access: yesPublications
Annotation and indexing of classical Chinese medical texts enable the extraction of core information, facilitating structured annotation and standardised indexing.
Sizhe Liu   +3 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

The Impact of Annotation on the Performance of Protein Tagging in Biomedical Text [PDF]

open access: yes, 2006
In this paper we discuss five different corpora annotated forprotein names. We present several within- and cross-dataset proteintagging experiments showing that different annotation schemes severelyaffect the portability of statistical protein taggers ...
Alex B.   +4 more
core  

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