Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann +17 more
wiley +1 more source
Promoting Middle School Students' Science Text Comprehension via Two Self-Generated "Linking" Questioning Methods. [PDF]
Sason H, Michalsky T, Mevarech Z.
europepmc +1 more source
This review summarizes artificial intelligence (AI)‐supported nonpharmacological interventions for adults with chronic rheumatic diseases, detailing their components, purpose, and current evidence base. We searched Embase, PubMed, Cochrane, and Scopus databases for studies describing AI‐supported interventions for adults with chronic rheumatic diseases.
Nirali Shah +5 more
wiley +1 more source
Children's Comprehension and Local-to-Global Recall of Narrative and Expository Texts
We examined underlying mechanisms for comprehension differences across expository and narrative text while controlling for factors confounded in the extant literature.
Fernando Romero +2 more
doaj
Objective The aim of this systematic review was to synthesize the economic impact of rheumatoid arthritis (RA) on households, health systems, and society in low‐ and middle‐income countries (LMICs). Methods Electronic databases such as PubMed, Web of Science, and CINAHL were searched using keywords related to RA and cost of illness.
Tadesse Gebrye +6 more
wiley +1 more source
Tracking your emotions: An eye-tracking study on reader's engagement with perspective during text comprehension. [PDF]
Child S, Oakhill J, Garnham A.
europepmc +1 more source
Knee Crepitus and Osteoarthritis Features in Young Adults Following Traumatic Knee Injury
Objective This study explored the association between knee crepitus and the presence, and worsening, of structural osteoarthritis features and self‐reported outcomes in young adults following traumatic knee injury. Methods One year following anterior cruciate ligament reconstruction (ACLR), 112 participants (41 female participants; median age 28 years ...
Jamon L. Couch +8 more
wiley +1 more source
Serum Soluble Mediator Signatures of Lupus Nephritis: Histologic Features and Response to Treatment
Objective Lupus nephritis (LN) management remains challenging, and novel noninvasive biomarkers are needed. This study quantified serum soluble mediators in the Accelerating Medicines Partnership (AMP) LN cohort to identify biomarkers of histologic features and treatment response.
Andrea Fava +48 more
wiley +1 more source
Impact of Positive Lifestyle Behaviors on Direct Health Care Cost Savings for Low Back Pain
Objective This study aimed to investigate the relationship between a previously purpose‐developed lifestyle behavior scale and health care cost savings related to low back pain (LBP). Methods This longitudinal study used data from the Australian Twin Back (AUTBACK) study. LBP and lifestyle behavior measures were collected at baseline. Physical activity
Ye Tian +8 more
wiley +1 more source
Expository Text Comprehension: Prior Knowledge and Working Memory
This paper examines the comprehension of general and disciplinary expository texts as a function of previous domain-specific knowledge, and working memory capacity. Novices or experts in psychology topics read a general expository text and a disciplinary
Saux, Gastón +2 more
doaj

