Results 191 to 200 of about 3,747,488 (307)

Stiffness‐Programmable Origami Robots With Tendon‐Driven Actuation via Multimaterial 3D Printing

open access: yesAdvanced Robotics Research, EarlyView.
Motion diversity is achieved in a tendon‐driven origami robot through programmable stiffness rather than modified actuation. Multimaterial 3D printing embeds soft creases, modular inserts redirect identical tendon inputs into distinct behaviors, and variable‐stiffness inserts enable real‐time switching.
Elisha Lerner, Jianguo Zhao
wiley   +1 more source

A Pentaradial and Bilateral Combined Photoreception System in the Sea Cucumber is Mediated by a Blue Light‐Sensitive R‐Opsin

open access: yesAdvanced Science, EarlyView.
The sea cucumber Holothuria leucospilota detects blue and adjacent wavelengths of light via an r‐opsin with a maximum absorption at 459 nm. In the oral tentacles, papillae, and tube feet, distinct light‐sensing structures with specialized morphologies are formed, constituting a unique pentaradial and bilateral combined photoreception system.
Jiasheng Huang   +20 more
wiley   +1 more source

Deep Contrastive Learning for High‐Throughput Prediction of Drug Resistance Mutations from Sequences

open access: yesAdvanced Science, EarlyView.
This study presents DeepMutDTA, a deep learning framework aimed at predicting mutation‐induced changes in protein‐drug interactions and prioritizing variants potentially linked to drug resistance. Trained on large‐scale data, it incorporates SimSiam‐MuTF, a label‐aware contrastive fine‐tuning strategy that encourages separation between WT and MT ...
Xiaowen Hu   +7 more
wiley   +1 more source

Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8+ T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen   +20 more
wiley   +1 more source

TEI P5 and Special Characters Outside Unicode

open access: yesJournal of the Text Encoding Initiative, 2013
Joel Fredell   +2 more
doaj   +1 more source

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