Results 101 to 110 of about 1,103,913 (306)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang +8 more
wiley +1 more source
, 2010 Many people are working on the Semantic Web with the main objective being to enhance web searches. Our proposal is a new research strategy based on the existence of a discrete set of semantic relations for the creation and exploitation of semantic ...
Alamo Lobo, Francisco Javier del +2 more
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A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Integrating Text Planning and Production
, 2008 While the task of language generation seems to separate quite naturally into the two aspects of language generation (text planning and text production), it is necessary to have the planning and the production interact at generator decision points in such
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ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Accessible email text production for AAC users
, 2002 Accessible email text production for AAC ...
Susan Keller (13051056) +1 more
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RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Location and design manual. Volume 3, Highway plans
, 1993 Updated quarterly.; Description based on: July 20, 2007 update; title from Home page caption (viewed on Oct.
Ohio. Dept. of Transportation. Office of Production
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Influence of playful texts on the production of texts by university students
, 2021 The research aimed to determine the influence of playful texts on the production of texts in the students of the III Cycle, Mention: Language and Literature of the Faculty of Education of UNSLG, the diagnosis were made that allowed to corroborate the limitations to produce texts of students and propose the use of playful texts recreationally convinced ...
Morón Hernandez, Julia Liliana +2 more
openaire +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers +7 more
wiley +1 more source