Results 51 to 60 of about 43,541,921 (287)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
, 2023 The broadside features the program of reception for the remains of Abraham Lincoln at the Great Western Depot on 3 May 1865. The program outlines the order in which individuals and groups stood during the reception as well as the processional route.https:
Committee on Reception of Remains
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RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
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, 2015 Syftet med avhandlingen ar att bidra till en okad kunskap om hur litterar socialisation genom undervisning i olika kontexter paverkar elevers satt att forhalla sig till en narrativ text och vilka k ...
Maritha Johansson
semanticscholar +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Auch wir lieben bekanntermaßen Daten. Daher ist Text+ natürlich auch bei der diesjährigen Love Data Week dabei, die vom 12. bis 16. Februar stattfindet.
Text+ Blog-Redaktion
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re3data und Text+ oder: Wie finden meine Daten den Weg in das richtige Repositorium?
, 2023 Autoren: Lukas Weimer, Stefan Buddenbohm Was ist re3data? Das Registry of Research Data Repositories (re3data) ist ein globales Verzeichnis für Forschungsdatenrepositorien aus verschiedenen Fachdisziplinen. Es hilft Datenerzeugenden bzw.
Text+ Mitglied
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
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Authors: Tina Ternes (University of Basel), Xenia Bojarski (University of Zurich) As cultural discourse has shifted increasingly to the internet, authentic data on book reception has become available in large volume and from readers all over the world ...
Text+ Mitglied
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