Results 71 to 80 of about 784,870 (334)

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Neurosemiotyka jako hermeneutyka kultury i literatury (Krótki komentarz do rozpraw Jana Kordysa)

Przestrzenie Teorii, 2007
This sketch presents the most important linguistic and semiological premises of the relatively new field of science, neurosemiotics, which is the research base of Jan Kordys' studies, who transformed it into a neurosemiotical hermeneutics of culture ...
Stanisław Balbus
doaj   +1 more source

Challenging Social Cognition Models of Adherence:Cycles of Discourse, Historical Bodies, and Interactional Order [PDF]

, 2015
Attempts to model individual beliefs as a means of predicting how people follow clinical advice have dominated adherence research, but with limited success.
Alexander F., Atkinson J. M., Bowker G., Charlotte Salter, Charmaz K., Christensen A. J., Cornwell J., Department of Health, Dunbar F., Duranti A., Fairclough N., Fiona Poland, Goffman E., Hymes D., Jamie Murdoch, Jane Cross, Maimonides M., McLeod C., Mishler E. G., Osler W., Peyrot M., Salter H. H., Scollon R., Silverman D., Sontag S.   +24 more
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Teisinių žinių bazių ir teisinių dokumentų izomorfizmo realizavimo metodas

Informacijos Mokslai, 2008
Dirbtinio intelekto ir kitų kompiuterinių technologijų naudojimas rengiant teisės aktus pagerina jų kokybę ir sutrumpina rengimo laiką. Viena iš problemų, su kuriomus susiduriama formalizuojant teisės aktus, yra izomorfizmo problema.
Laima Paliulionienė
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Bias Gender dalam Kewarisan Menurut Ulama Bugis [PDF]

, 2013
Continous dialogue between textualist and contextualist about formula of inheritance where textualist refers to universality of texts and contextualist base on particular background.
Yusuf, M. (Muhammad)
core   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

La pédagogie des discours scientifiques et techniques en contexte plurilingue

Langues & Cultures, 2020
Nous nous efforcerons de démontrer dans cet article quelques spécificités linguistiques de textes supports destinés pour une filière scientifique et technique en l’occurrence les sciences vétérinaires, et ce, pour en dégager les points saillants du fait ...
IMESSAOUDENE Mohamed Faouzi, KAOUADJI Charef Eddine   +1 more
doaj   +1 more source