Results 221 to 230 of about 371,752 (272)

Trackable Tolerogenic Macrophages Integrate PD‐L1 and Rapamycin Signaling to Suppress Alloimmune Responses in Transplantation

Advanced Science, EarlyView.
We developed a macrophage‐based therapeutic platform, termed trackable tolerogenic macrophages (TTM), for dual‐function immunomodulation and visualization in vivo. TTM cells were engineered to overexpress PD‐L1, incorporate bioorthogonal cell surface tags, and load rapamycin for sustained release.
Yihui Wang, Yuan Song, Yuji Xie, Junmin Zhang, Jing Liu, Wenyuan Wang, Ying Xu, Wenqian Wu, Wuqi Zhou, Qiaofeng Jin, Jing Wang, Yali Yang, Li Zhang, Tang Gao, Mingxing Xie   +14 more
wiley   +1 more source

Comparative Study on the Hardness, Adhesiveness, and Cohesiveness of Ingredients on the Basis of IDDSI Levels and Ingredient Selection. [PDF]

Food Sci Nutr
Chen M, Duan J, Cheng Y, Yan J, Shi L, Yuan L.   +5 more
europepmc   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

Texture-based image feature analysis for the classification of oral squamous cell carcinoma using machine learning approach. [PDF]

BMC Oral Health
Bahaa S, Ramadan O, Darwish ZE, El-Fiky E, Saleh MM.   +4 more
europepmc   +1 more source

Leaky‐Integrate‐Fire Neuron via Synthetic Antiferromagnetic Coupling and Spin‐Orbit Torque

Advanced Science, EarlyView.
A spintronic leaky‐integrate‐and‐fire neuron is realized using Spin Orbit Torque driven domain‐wall motion for integration and synthetic antiferromagnetic coupling for the leaky process. The specialized Hall‐bar geometry enables controlled DW dynamics, achieving repeatable integration and firing events. This compact, CMOS‐compatible design highlights a
Badsha Sekh, Durgesh Kumar, Hasibur Rahaman, Ravi Shankar Verma, Ramu Maddu, Jianpeng Chan, Wai Lum William Mah, Stuart S. P. Parkin, S. N. Piramanayagam   +8 more
wiley   +1 more source

Machine learning-based classification of histological subtypes of invasive breast cancer using MRI contralateral breast texture features. [PDF]

Sci Rep
Nuzla AN, Nabeel AKM, Nirmal WAS, Hewavithana PB, Jayatilake ML.   +4 more
europepmc   +1 more source

Room‐Temperature Magnetic Skyrmions and Intrinsic Anomalous Hall Effect in a Nodal‐Line Kagomé Ferromagnet MnRhP

Advanced Science, EarlyView.
MnRhP has been identified as a novel kagomé magnet that hosts magnetic skyrmions above room temperature and exhibits a large intrinsic anomalous Hall effect. The latter originates from Berry curvature associated with gapped nodal lines, establishing MnRhP as a promising platform for exploring high‐temperature topological phenomena in both real and ...
Kosuke Karube, Ming‐Chun Jiang, Lukas Keller, Jonathan S. White, Yi Ling Chiew, Xiuzhen Yu, Guang Yu Guo, Ryotaro Arita, Yoshinori Tokura, Yasujiro Taguchi   +9 more
wiley   +1 more source

Quantitative Imaging Advances in HPV-Positive Oropharyngeal Carcinoma. [PDF]

Cancers (Basel)
Farrell D, Bahig H, Khor R, Kowalski LP, de Bree R, Eisbruch A, Bollen H, Lopez F, Sreeram MP, Guntinas-Lichius O, Rodrigo JP, Saba NF, Rao KN, Nuyts S, Araújo ALD, Ferlito A, Ng SP.   +16 more
europepmc   +1 more source

Patient‐Derived 3D‐Bioprinted Intrahepatic Cholangiocarcinoma Models Recapitulate Tumor Autologous Traits and Predict Personalized Adjuvant Therapy

Advanced Science, EarlyView.
Leveraging 3D bioprinting, this study establishes patient‐derived in vitro models of intrahepatic cholangiocarcinoma. These models faithfully recapitulate the histopathology, molecular profiles, and genomic characteristics of the original patient tumors.
Yuce Lu, Liwei Du, Minghao Sun, Kai Zhang, Mingchang Pang, Shangze Jiang, Jiaxun Dong, Xiyue Liu, Bao Jin, Fu Xu, Hang Sun, Jiangang Zhang, Huiyu Yang, Xiaobo Yang, Xin Lu, Yiyao Xu, Haitao Zhao, Shunda Du, Xinting Sang, Yongchang Zheng, Lei Zhang, Xueshuai Wan, Huayu Yang, Yilei Mao   +23 more
wiley   +1 more source

Qualitative Insights From Practicing Speech and Language Therapists on Key Textural Attributes of Transitional Foods for Dysphagia Management. [PDF]

J Texture Stud
Kwong SL, Lee JMW, Goh SM, Lim VPC, Stoyanov SD, Nishinari K.   +5 more
europepmc   +1 more source