Results 71 to 80 of about 85,483 (193)

Promoting Autophagy Mitigates Stress‐Induced Remodeling in Patient iPSC‐CMs with the Phospholamban R9C Mutation

Advanced Science, Volume 13, Issue 7, 3 February 2026.
The Phospholamban (PLN) R9C mutation reduces SERCA2a binding, increasing calcium recycling and baseline contractility. However, the excess of free PLN promotes pentamer formation, limiting phosphorylation and blunting β‐adrenergic signaling. Under cardiac stress, enhanced functional demands overwhelm proteostasis in PLN R9C cells, leading to misfolded ...
Qi Yu, Yawei Shen, Robert J. Barndt, Karim Sallam, Ying Tang, Cameron E. Brown, Xiao Li, Stephen Y. Chan, Joseph C. Wu, Qing Liu, Haodi Wu   +10 more
wiley   +1 more source

AI‐enhanced Centiloid quantification of amyloid PET images

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION The Centiloid scale is the standard for amyloid (Aβ) PET quantification in research and clinical settings. However, variability between tracers and scanners remains a challenge. METHODS This study introduces DeepSUVR, a deep learning method to correct Centiloid quantification, by penalizing implausible longitudinal trajectories ...
Pierrick Bourgeat, Jurgen Fripp, Leo Lebrat, Ying Xia, Azadeh Feizpour, Timothy Cox, Georgios Zisis, Ashley Gillman, Manu S. Goyal, Duygu Tosun, Tammie LS. Benzinger, Pamela LaMontagne, Michael Breakspear, Michelle K. Lupton, Cathy Short, Robert Adam, Joanne S. Robertson, Reisa Sperling, Sid E. O'Bryant, Sterling C. Johnson, Clifford R. Jack Jr, Christopher G. Schwarz, Frederik Barkhof, Gill Farrar, Ariane Bollack, Lyduine E. Collij, Susan Landau, Robert Koeppe, for the Alzheimer's Disease Neuroimaging Initiative, OASIS3, the A4/LEARN Study Team, the AMYPAD consortium, The Health and Aging Brain Study (HABS‐HD) Study Team, Mayo Clinic Study of Aging, WRAP, ADNI‐DOD, PISA, ADNeT, the AIBL research group, John C. Morris, Michael W. Weiner, Victor L. Villemagne, Colin L. Masters, Christopher C. Rowe, Vincent Dore   +44 more
wiley   +1 more source

Comparison between PA and PWI/TFM Techniques for Non-Destructive Testing of Carbon Steel Weld

e-Journal of Nondestructive Testing
The Total Focusing Method (TFM) technique is an advanced Non-Destructive Testing (NDT) Ultrasonic Testing (UT) technique well known for its representative images of high resolution.
Weina Ke
doaj   +1 more source

Testing and comparing conditional CAPM with a new approach in the cross-sectional framework [PDF]

, 2014
This study examines the conditional relationship between beta and return for stocks traded on S&P 500 for the period from July 2001 to June 2011. The portfolios formed based on the Book value per share and betas using monthly data.
Alexandridis, Antonis, Messis, P, Zapranis, Achilleas   +2 more
core  

Mapping Collective Forces of Lung Cancer Spheroids Using Traction Force Microscopy

Biotechnology and Bioengineering, Volume 123, Issue 2, Page 449-464, February 2026.
The application of conventional TFM to cancer spheroids revealed not only a size‐dependent traction force when spheroids were in non‐wetting transition state, but also a positive correlation of this force with the spheroid dispersion capacity. Moreover, the onset of spheroid dispersion was accompanied by a pronounced suppression of spheroid traction ...
Qing Zhang, Jiaqi Chen, Zhaoxu Zhang, Weili Liu   +3 more
wiley   +1 more source

Left-orderable fundamental group and Dehn surgery on genus one two-bridge knots

, 2013
For any hyperbolic genus one 2-bridge knot in the 3-sphere, we show that the resulting manifold by $r$-surgery on the knot has left-orderable fundamental group if the slope $r$ lies in some range which depends on the knot.Comment: 19 pages, 2 figures ...
Hakamata, Ryoto, Teragaito, Masakazu
core   +1 more source

Heart‐On‐a‐Chip with Integrated Ultrasoft Mechanosensors for Continuous Measurement of Cell‐ and Tissue‐Scale Contractile Stresses

Small, Volume 22, Issue 9, 12 February 2026.
We present a heart‐on‐a‐chip platform embedded with ultrasoft mechanosensors for real‐time, multi‐scale stress mapping in engineered cardiac tissues. The system enables simultaneous quantification of local cell‐generated stresses and global tissue contractile forces.
Ali Mousavi, Christina‐Marie Boghdady, Shihao Cui, Sabra Rostami, Amid Shakeri, Naimeh Rafatian, Mark Aurousseau, Gregor Andelfinger, Milica Radisic, Christopher Moraes, Houman Savoji   +10 more
wiley   +1 more source

Superparamagnetic nanoparticle ensembles

, 2012
Magnetic single-domain nanoparticles constitute an important model system in magnetism. In particular ensembles of superparamagnetic nanoparticles can exhibit a rich variety of different behaviors depending on the inter-particle interactions.
Allwood, Batlle, Bedanta, Benitez, Berkovsky, Binney, Blundell, Brown, Chen, Chen, Daughton, Denardin, Dormann, El-Hilo, Ge, Hauschild, Iglesias, Jeong, Jiles, Jönsson, Kakazei, Kleemann, Kodama, Luis, Lyubchanskii, Moerup, Moerup, Mydosh, Nogués, Néel, Néel, O. Petracic, Odenbach, O’Handley, Pankhurst, Petracic, Petracic, Petracic, Petracic, Pfeiffer, Provenzano, Rosensweig, Sahoo, Sahoo, Sahoo, Sankar, Scheinfein, Sharrock, Siegmann, Skomski, Skomski, Sun, Terris, Wolf   +53 more
core   +1 more source

Left‐displaced abomasum in a late‐pregnant goat

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract A female goat in late gestation was presented to a veterinary teaching hospital due to the sudden onset of abdominal distention and signs of cardiovascular depression. On admission, the goat exhibited an overloaded rumen, which seemed noticeably distant from the abdominal wall on the left‐hand side.
Eva Petzl, Katja Voigt, Viktoria Balasopoulou, Maria Beer, Florian M. Trefz   +4 more
wiley   +1 more source

Programa de prevención del burnout y fatiga por compasión para profesionales sanitarios que atienden pérdidas perinatales.

Psicosomática y Psiquiatría, 2022
M.P. Plata Iglesias
doaj   +1 more source