Results 91 to 100 of about 4,323 (259)

Convergence of Low‐Fertility Policies Beyond Policy Transfer: A Comparative Analysis of Korea and Hungary

Public Administration and Development, EarlyView.
ABSTRACT This study compares policy responses to persistent low fertility in Korea and Hungary, two countries facing similar demographic pressures but embedded in distinct institutional settings. It asks whether the diffusion of pronatalist policies has produced convergence in the design, implementation, and effects of fertility policy in these cases ...
Kilkon Ko, M. Jin Lee, Tamás Pesuth
wiley   +1 more source

Carbon dots as a smart nanoplatform for the blood‐brain barrier penetration and ischemic stroke therapy

Responsive Materials, EarlyView.
This review presents the structure and transport routes of the blood‐brain barrier, summarizes the ischemic stroke pathophysiological cascade, and discusses the BBB‐crossing mechanisms and multitarget therapeutic effects of carbon dots, demonstrating their promising theranostic potential for ischemic stroke.
Yanhan Huang, Xuan Hou, Haiping Zhao, Qi Kong, Xiayan Wang, Xiaokun Geng, Zaicheng Sun   +6 more
wiley   +1 more source

Achieve Sustainability by Easing Population to 4 Billion by 2200

Sustainable Development, EarlyView.
ABSTRACT The past century of massive increases in human population and resource use has seen many undesirable environmental effects, ranging from biodiversity loss to climate change. But a research gap exists, as the ultimate causes are often not described with precision or mentioned at all.
Mark Keegan, Anastasia Pseiridis, Philip Cafaro, Jane O'Sullivan, William Rees, Estelle Monique Sidze, Lawrence Whitmore, Enrique J. Derlindati, Mohammad Mainul Islam, Khaoula Houssini, S. Irudaya Rajan   +10 more
wiley   +1 more source

Reticulocyte transferrin receptor (TfR) expression and contribution to soluble TfR levels.

Haematologica, 2001
Transferrin receptor (TfR) expression in erythroid cells is regulated by a number of factors, including iron status and erythropoietin (Epo) stimulation. However, the impact of these factors on reticulocyte TfR expression in vivo has never been studied. A soluble form of TfR (sTfR) is present in serum in proportion to the mass of cellular TfR. Although
R'Zik, Samir, Loo, Martine, Beguin, Yves
openaire   +2 more sources

Artificial intelligence empowers targeted protein degradation: Core technological innovations, multi‐scenario applications, and translational prospects

Smart Molecules, EarlyView.
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin, Rui Peng, Guangshuai Zhang, Si Yan, Jin Xiao, Zishu Liu, Ziyu Tan, Qingqing Xie, Shangjie Li, Wei Luo, Xiaohe Xiao   +10 more
wiley   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

VIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin, Galyna Bila, Ileana Manduteanu, Rostyslav Bilyy   +3 more
wiley   +1 more source

Tangible fixed assets accounting according to Turkish financial reporting standards (TFRS) and TFRS for SMEs

, 2012
Yüksek Lisans Teziİşletmelerin, küreselleşmenin bir sonucu olarak sınırlarının ortadan kalkmasıyla daha karmaşık bir yapıya sahip olmaları, finansal raporlamada da köklü değişimleri zorunlu kılmıştır.
Sarısoy, Özkan
core   +1 more source

Safety and Efficacy of Deucravacitinib in Japanese Patients With Moderate to Severe Plaque Psoriasis: 5‐Year Analysis of the Phase 3 POETYK PSO‐1, PSO‐4, and Long‐Term Extension Trials

The Journal of Dermatology, EarlyView.
ABSTRACT Deucravacitinib, an oral, selective tyrosine kinase 2 inhibitor, is approved in multiple countries for the treatment of moderate to severe plaque psoriasis, as well as generalized pustular and erythrodermic psoriasis in Japan. Deucravacitinib 6 mg once daily was efficacious and well tolerated through 3 years in the pooled population of ...
Yukari Okubo, Akimichi Morita, Yayoi Tada, Shinichi Imafuku, April W. Armstrong, Andrew Blauvelt, John Vaile, Zoran Popmihajlov, Janice Li, Rajesh Sawant, Katsuyoshi Habiro, Katsuki Tsuritani, Mamitaro Ohtsuki   +12 more
wiley   +1 more source

Investigation of Different CNN-Based Models for Improved Bird Sound Classification

IEEE Access, 2019
Automatic bird sound classification plays an important role in monitoring and further protecting biodiversity. Recent advances in acoustic sensor networks and deep learning techniques provide a novel way for continuously monitoring birds.
Jie Xie, Kai Hu, Mingying Zhu, Jinghu Yu, Qibing Zhu   +4 more
doaj   +1 more source

TFRS 15 müşteri sözleşmelerinden hasılat standardının incelenmesi ve telekomünikasyon sektörü açısından değerlendirilmesi

, 2019
TMS 18 Hasılat Standardındaki belirsizlikleri ve yetersizlikleri ortadan kaldıran TFRS 15 Müşteri Sözleşmelerinden Hasılat Standardı, bazı sektörlerde hasılatın ve çeşitli unsurların muhasebeleştirilmesinde izlenen ilke ve yöntemleri etkileyecektir ...
Erdoğan, Ali Haydar
core