Results 41 to 50 of about 2,345 (208)
Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis
Advanced NanoBiomed Research, EarlyView.Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia +10 more
wiley +1 more source
Advanced NanoBiomed Research, EarlyView.Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi +6 more
wiley +1 more source
Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis
Animal Research and One Health, EarlyView.Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang +11 more
wiley +1 more source
Canine parvovirus-like particles, a novel nanomaterial for tumor targeting
Journal of Nanobiotechnology, 2006 Specific targeting of tumor cells is an important goal for the design of nanotherapeutics for the treatment of cancer. Recently, viruses have been explored as nano-containers for specific targeting applications, however these systems typically require ...
Destito Giuseppe +3 more
doaj +1 more source
Arthritis &Rheumatology, EarlyView.Objective Regeneration and expansion of Treg by low‐dose interleukin‐2 (IL‐2) therapy is considered a potential treatment strategy for a wide range of autoimmune diseases. To provide a pathophysiologically‐based rationale for low‐dose IL‐2 therapy, we investigated whether reversible defects in the Treg–IL‐2 axis emerge in inflammatory myopathies ...
Justus Ohmes +10 more
wiley +1 more source
The Ubiquity of Twisted Flux Ropes in the Quiet Sun
The Astrophysical Journal LettersModels and observations have demonstrated that twisted flux ropes (TFRs) play a significant role in the structure and eruptive dynamics of active regions.
Tahar Amari +8 more
doaj +1 more source
Sosyal Ekonomik Araştırmalar Dergisi, 2014 Muhasebe uygulamalarına yön veren kurallar bütünü olarak adlandırılan standartların temeli muhasebe ilkelerine, muhasebe ilkelerinin temeli ise muhasebenin temel kavramlarına dayanmaktadır.
Yunus Ceran, Merve Öz
doaj +1 more source
Mixed lineage kinase 3 mediates SARS‐CoV‐2‐induced kidney injury via the Hsp70‐IL‐17A axis
Interdisciplinary Medicine, EarlyView.Kidney samples from patients infected with severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) showed upregulated expression and activity of Mixed Lineage Kinase (MLK3). Based on the mechanistic studies, we identified MLK3 as a critical player in promoting SARS‐CoV‐2‐induced kidney injury.
Sandeep Kumar +18 more
wiley +1 more source
Cumhuriyet Üniversitesi İktisadi ve İdari Bilimler Dergisi, 2015 Yeni Türk Ticaret Kanunu ile muhasebe kayıtlarının tutulması ve finansal tabloların düzenlenmesi, Uluslararası Muhasebe Standartları (UMS=IAS=International Accounting Standards) ve Uluslararası Finansal Raporlama Standartları (UFRS=IFRS=International ...
Şakir Dızman
doaj
Sosyal Ekonomik Araştırmalar Dergisi, 2014 Türkiye’de kamuya hesap verme yükümlülüğü bulunan birçok işletme günümüzde Türkiye Muhasebe/Finansal Raporlama Standartlarını (TMS/TFRS) uygulamaktadır.
Ali Deran +2 more
doaj +1 more source