Results 81 to 90 of about 2,345 (208)
TecnoLógicas, 2011 En el presente trabajo se propone una metodología para la reducción de dimensión en representaciones tiempo frecuencia (TFRs) enfocada a la clasificación de bioseñales no estacionarias, que trata directamente su cantidad de datos irrelevantes y ...
Juan D. Martínez-Vargas +2 more
doaj
The Fertility Effects of Reducing Implicit Childcare Subsidies: The Case of School Schedules
Journal of Policy Analysis and Management, Volume 45, Issue 4, Fall 2026.ABSTRACT Despite governments’ efforts to raise fertility through family‐support policies, birth rates continue to decline in high‐ and middle‐income countries. Some policies designed for other purposes, however, may function as implicit childcare subsidies.
Álvaro Muñiz‐Fernández
wiley +1 more source
Chemistry – A European Journal, Volume 32, Issue 30, 13 August 2026.ABSTRACT Fluorouracil‐platinum(IV) prodrugs represent a novel class of multimechanistic chemotherapeutics with enhanced anticancer potential. The prodrugs PtIVP‐5FUMeOBut and PtIV56‐5FUMeOBut were actualized by derivatising the clinical drug 5‐fluorouracil (5FU) and coordinating it to platinum(IV) complexes, leveraging the established cytotoxicity of ...
Maria George Elias +9 more
wiley +1 more source
FEBS Open Bio, Volume 16, Issue 8, Page 1501-1508, August 2026.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
Advanced Science, Volume 13, Issue 43, 3 August 2026.Brown adipocyte sheets are engineered to protect the heart against myocardial ischemia–reperfusion injury by restraining ferroptosis. Upon transplantation onto the cardiac surface, they improve cardiac function, limit infarction and fibrosis, and enhance angiogenesis.
Lifu Sun +6 more
wiley +1 more source
A Plug‐and‐Play Platform for Customizing Multivalent Degraders and Degrader‐Drug Conjugates
Advanced Science, Volume 13, Issue 44, 7 August 2026.Membrane proteins remain challenging targets for conventional TPD approaches. Here, the authors develop UPTAB, a modular platform leveraging ultrahigh‐affinity orthogonal Im/CL protein pairs for lysosomal degradation of membrane proteins. Mono‐targeted (Type‐I), dual‐targeted (Type‐II), and tri‐targeted (Type‐III) UPTABs enable simultaneous degradation
Mengqing Zhao +7 more
wiley +1 more source
European Journal of Immunology, Volume 56, Issue 8, August 2026.T follicular helper (Tfh) cells support germinal center (GC) B cells, generating long‐lived antibody‐secreting and memory B cells. RNA‐binding proteins likely fine‐tune Tfh function, but selective deletion of ZFP36L1 from Tfh cells alters neither their differentiation nor GC responses. This suggests further redundancy within the ZFP36 family.
Helena A. Carslaw +6 more
wiley +1 more source
Epilepsia Open, Volume 11, Issue 4, Page 1095-1110, August 2026.Abstract Objective Epilepsy is a prevalent chronic neurological disorder characterized by abnormal neuronal electrical activity. The primary treatment modality for individuals with epilepsy (PWE) is antiseizure medication (ASM). The multiple potential factors contributing to treatment resistance in epilepsy may be attributed to the inability of ASMs to
Priya Kannan Varshini +9 more
wiley +1 more source
The Impact of Oral‐Gut Microbiota Structure and Its Manipulation on RA Development and Management
Food Science &Nutrition, Volume 14, Issue 8, August 2026.(A) Schematic representation of oral–gut microbiota composition in health and rheumatoid arthritis (RA), highlighting the enrichment of beneficial microorganisms (green) under healthy conditions and the expansion of pathogenic microorganisms (orange) in RA‐associated dysbiosis.
Parisa Ahmadi +8 more
wiley +1 more source