Results 41 to 50 of about 7,034,149 (293)

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Ideophones: honing in on a descriptive and typological concept

Linguistic Typology at the Crossroads
This paper introduces the special issue of Linguistic Typology at the Crossroads, entitled “Ideophones: honing in on a descriptive and typological concept”, edited by Aimée Lahaussois, Julie Marsault and Yvonne Treis.
Julie Marsault, Aimée Lahaussois, Yvonne Treis   +2 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Carré Louis et Loute Alain (dir.), Donner, reconnaître, dominer. Trois modèles en philosophie sociale, Presses universitaires du Septentrion, coll. « Philosophie », 2016, 232 p.

, 2017
Cet ouvrage collectif propose une réflexion sur la manière dont s’articulent les modèles du don, de la reconnaissance et de la domination. Entre dialogue et confrontation, sa dimension plurielle nous invite à penser et à interroger autrement ces théories
Facon, Héloïse, Héloïse Facon
core   +1 more source

Extended Theories of Gravity [PDF]

, 2011
Extended Theories of Gravity can be considered as a new paradigm to cure shortcomings of General Relativity at infrared and ultraviolet scales. They are an approach that, by preserving the undoubtedly positive results of Einstein’s theory, is aimed to ...
S. Capozziello, M. Laurentis
semanticscholar   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

The sound roots of Umóⁿhoⁿ

Linguistic Typology at the Crossroads
This paper presents a corpus-based study of lexemes denoting sounds in Umóⁿhoⁿ (oma), a Siouan language of North America. I take as a starting point a list of sound-denoting verbal roots (in short: “sound roots”), presented as onomatopoeia in a paper by ...
Julie Marsault
doaj   +1 more source

Metric reconstruction from celestial multipoles

Journal of High Energy Physics, 2022
The most general vacuum solution to Einstein’s field equations with no incoming radiation can be constructed perturbatively from two infinite sets of canonical multipole moments, which are found to be mapped into each other under gravitational electric ...
Geoffrey Compère, Roberto Oliveri, Ali Seraj   +2 more
doaj   +1 more source

Biological roles of oligosaccharides: all of the theories are correct

Glycobiology, 1993
Many different theories have been advanced concerning the biological roles of the oligosaccharide units of individual classes of glycoconjugates. Analysis of the evidence indicates that while all of these theories are correct, exceptions to each can also
A. Varki
semanticscholar   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source