Results 51 to 60 of about 5,220,571 (262)

El verde vacila en pintar hojas, ¿el rojo aceptará pintar sangre? La literatura y el compromisoen Sartre y Adorno

open access: yesIdeas y Valores, 2015
Para responder a la pregunta: ¿Qué es la literatura?, Sartre propone el concepto deunidad como su característica exclusiva que la relaciona con la sociedad por la víadel compromiso.
Maya Claudia María
doaj  

Werkstofftechnik für Erstsemester im PBL-Design - konsequent kompetenzorientiert

open access: yesZeitschrift für Hochschulentwicklung, 2016
Lehrende technischer Fächer suchen häufig nach Wegen weg vom Frontalunterricht. Gleichzeitig bestehen Bedenken, dass z. B. Gruppenarbeit in großen Lehrveranstaltungen nicht die notwendige verbindliche Dynamik annimmt.
Michael Hagen, Birgit Szczyrba
doaj   +1 more source

Maximising Distribution Grid Utilisation by Optimising E-Car Charging Using Smart Meter Gateway Data

open access: yesEnergies, 2023
The transition towards climate neutrality will result in an increase in electrical vehicles, as well as other electric loads, leading to higher loads on electrical distribution grids.
André Ulrich   +4 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Protective efficacy of combined monoclonal antibody docaravimab and miromavimab preparation against classical rabies virus: A preclinical study in BALB/c mice

open access: yesБиопрепараты: Профилактика, диагностика, лечение
INTRODUCTION. Medicinal products based on monoclonal antibodies (mAbs) is one of the promising options for post-exposure rabies prophylaxis. Since Russian pharmaceutical market does not offer anti-rabies mAbs, a combined docaravimab and miromavimab ...
S. V. Borisevich   +11 more
doaj   +1 more source

Clinical Evaluation of Mobile Medical Apps

open access: yesCurrent Directions in Biomedical Engineering, 2018
Computer applications in medicine are very important. However, there are differences in quality of such software, which periodically led to discussions about safety, regulation, and registration of software applications. Today, the admission procedure of
Michael Scholtes   +4 more
doaj   +1 more source

MALIS Reloaded

open access: yeso-bib. Das offene Bibliotheksjournal, 2021
Gerade für die Studiengänge der Bibliotheks- und Informationswissenschaft ist eine kontinuierliche Überprüfung und Aktualisierung der Studieninhalte angesichts der hohen Entwicklungsdynamik der digitalen Transformation und ihrer Auswirkungen auf die ...
Inka Tappenbeck, Haike Meinhardt
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Standardization of building technology on demand via robotic [PDF]

open access: yesE3S Web of Conferences, 2019
Although the basic installation arrangement and sequence within Technical Building Equipment, based on generation, distribution and transfer of energy quantities, has remained virtually unchanged for some time, this essentially grid-connected world of ...
Henne Andreas, Kloster Nina
doaj   +1 more source

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