Results 321 to 330 of about 10,640,595 (395)

Th1/Th2 Cells and Associated Cytokines in Acute Hepatitis E and Related Acute Liver Failure. [PDF]

J Immunol Res, 2020
Wu J, Guo Y, Lu X, Huang F, Lv F, Wei D, Shang A, Yang J, Pan Q, Jiang B, Yu J, Cao H, Li L.   +12 more
europepmc   +1 more source

Inducible Expression of a Th2-Type CC Chemokine Thymus- and Activation-Regulated Chemokine by Human Bronchial Epithelial Cells [PDF]

, 2000
Takashi Sekiya, Misato Miyamasu, Masako Imanishi, Hirokazu Yamada, Toshiharu Nakajima, Masao Yamaguchi, Takao Fujisawa, Ruby Pawankar, Yasuyuki Sano, Ken Ohta, Akira Ishii, Yutaka Morita, Kazuhiko Yamamoto, Kouji Matsushima, Osamu Yoshie, Koichi Hirai   +15 more
openalex   +1 more source

Beyond the Toll‐Like Receptor 4. Structure‐Dependent Lipopolysaccharide Recognition Systems: How far are we?

ChemMedChem, Volume 20, Issue 6, March 15, 2025.
This review goes beyond the famous MD‐2/TLR4‐mediated recognition of LPS, pointing the attention on other immune detection systems and their impact on human physiology and pathology. Understanding these additional pathways is key for the development of pharmacologically active molecules to modulate the immune response and to conceive new strategies to ...
Stefania De Chiara, Luca De Simone Carone, Roberta Cirella, Emanuela Andretta, Alba Silipo, Antonio Molinaro, Marcello Mercogliano, Flaviana Di Lorenzo   +7 more
wiley   +1 more source

ALLOGENEIC LIVER-DERIVED DENDRITIC CELL PROGENITORS SELECTIVELY INDUCE Th2 CYTOKINE RESPONSES IN VITRO AND IN VIVO

, 1999
Ajai Khanna, Adrián E. Morelli, Cuiping Zhong, Angus W. Thomson, Liwei Lu   +4 more
openalex   +1 more source

First‐in‐Human Phase 1 Study to Evaluate the Clinical Pharmacology Properties of RBN‐3143, a Novel Inhibitor of Mono‐Adenosine Diphosphate Ribosyltransferase‐PARP14

Clinical Pharmacology in Drug Development, EarlyView.
Abstract RBN‐3143 is an inhibitor of PARP14 in development for inflammatory diseases. Multiple assessments were conducted to evaluate the clinical pharmacology properties of RBN‐3134. A randomized, double‐blind, placebo‐controlled study assigned healthy volunteers (HVs) to single ascending doses (SADs) (25‐1000 mg) or multiple ascending doses (MADs ...
Thomas M. Polasek, Alexandra Cole, Viviana Bozón, Erika Manyak, Jonathan Novak, Barbara Yang, Briohny A. Johnston, Sudha Parasuraman, Kushal J. Paneliya, Virna Schuck   +9 more
wiley   +1 more source

Identification of CRTH2 as a New PPARγ-Target Gene in T Cells Suggested CRTH2 Dependent Conversion of T_h2 Cells as Therapeutic Concept in COVID-19 Infection. [PDF]

Immunotargets Ther
Becker A, Röhrich K, Leske A, Heinicke U, Knape T, Kannt A, Trümper V, Sohn K, Wilken-Schmitz A, Neb H, Adam EH, Laux V, Parnham MJ, Onasch V, Weigert A, Zacharowski K, von Knethen A.   +16 more
europepmc   +1 more source

Biomarkers of lung congestion and injury in acute heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 781-789, April 2025.
Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi, Gabriele Novello, Francesca Bursi, Anna Caretti, Noemi Furlotti, Ross Arena, Paola Argiento, Julio Núñez, Antoni Bayes‐Genis, Marco Metra   +9 more
wiley   +1 more source

Author Correction: Cutaneous T cell lymphoma atlas reveals malignant T_H2 cells supported by a B cell-rich tumor microenvironment. [PDF]

Nat Immunol
Li R, Strobl J, Poyner EFM, Balbaa A, Torabi F, Mazin PV, Chipampe NJ, Stephenson E, Ramírez-Suástegi C, Shanmugiah VBM, Gardner L, Olabi B, Coulthard R, Botting RA, Zila N, Prigmore E, Gopee NH, Chroscik MA, Kritikaki E, Engelbert J, Goh I, Chan HM, Johnson HF, Ellis J, Rowe V, Tun W, Reynolds G, Yang D, Foster AR, Gambardella L, Winheim E, Admane C, Rumney B, Steele L, Jardine L, Nenonen J, Pickard K, Lumley J, Hampton P, Hu S, Liu F, Liu X, Horsfall D, Basurto-Lozada D, Grimble L, Bacon CM, Weatherhead SC, Brauner H, Wang Y, Bai F, Reynolds NJ, Allen JE, Jonak C, Brunner PM, Teichmann SA, Haniffa M.   +55 more
europepmc   +1 more source

Investigation into imbalance of Th1/Th2 cells in cirrhotic, hypersplenic rats. [PDF]

J Int Med Res, 2020
Lv Y, Li Y, Liu N, Dong Y, Deng J.
europepmc   +1 more source

GATA-3 promotes Th2 responses through three different mechanisms: induction of Th2 cytokine production, selective growth of Th2 cells and inhibition of Th1 cell-specific factors

Cell Research, 2006
Jinfang Zhu, H. Yamane, J. Cote-Sierra, Liying Guo, W. Paul   +4 more
semanticscholar   +1 more source