Results 21 to 30 of about 167,135 (249)

Synthesis, in Vitro Pharmacology, and Molecular Modeling of Very Potent Tacrine−Huperzine A Hybrids as Acetylcholinesterase Inhibitors of Potential Interest for the Treatment of Alzheimer's Disease [PDF]

open access: yes, 1999
Eleven new 12-amino-6,7,10,11-tetrahydro-7,11-methanocycloocta[b]quinoline derivatives [tacrine (THA)−huperzine A hybrids, rac-21−31] have been synthesized as racemic mixtures and tested as acetylcholinesterase (AChE) inhibitors.
Badia, Albert   +21 more
core   +1 more source

Prophylactic cable prevents tapered titanium stem subsidence with 2 cm of stem-cortical engagement in a cadaveric model

open access: yesBone & Joint Open, 2023
Aims: When performing revision total hip arthroplasty using diaphyseal-engaging titanium tapered stems (TTS), the recommended 3 to 4 cm of stem-cortical diaphyseal contact may not be available. In challenging cases such as these with only 2 cm of contact,
William Xiang   +7 more
doaj   +1 more source

Prevention of infection in primary THA and TKA

open access: yesEFORT Open Reviews, 2020
Rates of peri-prosthetic joint infection (PJI) in primary total hip and total knee arthroplasty range between 0.3% and 1.9%, and up to 10% in revision cases.
P. Dobson, M. Reed
semanticscholar   +1 more source

Demographic characteristics of patients undergoing conventional stemmed THA or resurfacing THA by bearing surface.

open access: yes, 2022
Demographic characteristics of patients undergoing conventional stemmed THA or resurfacing THA by bearing surface.
Stephen E. Graves (11068448)   +3 more
core   +1 more source

Less early subsidence of cemented Exeter short stems compared with cemented Exeter standard stems in Dorr type A femurs: a radiostereometry study with minimum five years’ follow-up

open access: yesBone & Joint Open, 2023
Aims: The Exeter short stem was designed for patients with Dorr type A femora and short-term results are promising. The aim of this study was to evaluate the minimum five-year stem migration pattern of Exeter short stems in comparison with Exeter ...
Peter B. Jørgensen   +5 more
doaj   +1 more source

Global diversity in bearings in primary THA

open access: yesEFORT Open Reviews, 2020
Choice of articulating materials, head size and the design of the articulation will become decisive for the long-term performance of a total hip arthroplasty (THA) and especially in terms of risk for dislocation and wear-related problems. Here we account
G. Tsikandylakis   +3 more
semanticscholar   +1 more source

Recent advances in the involvement of long non-coding RNAs in neural stem cell biology and brain pathophysiology

open access: yesFrontiers in Physiology, 2014
Exploration of non-coding genome has recently uncovered a growing list of formerly unknown regulatory long non-coding RNAs (lncRNAs) with important functions in stem cell pluripotency, development and homeostasis of several tissues. Although thousands of
Daphne eAntoniou   +2 more
doaj   +1 more source

Is Geographic Socioeconomic Disadvantage Associated with the Rate of THA in Medicare-aged Patients?

open access: yesClinical Orthopaedics and Related Research, 2020
BACKGROUND Disparities in THA use may lead to inequitable care. Prior research has focused on disparities based on individual-level and isolated socioeconomic and demographic variables.
Rafa Rahman   +3 more
semanticscholar   +1 more source

THA in patients with neglected acetabular fractures

open access: yes, 2022
Introduction: Total hip arthroplasty (THA) outcomes in patients with neglected acetabular fractures are less favourable compared to THA for osteoarthritis or inflammatory arthritis.
Sushil Singh   +11 more
core   +1 more source

Patient mortality after primary THA.

open access: yes, 2021
Kaplan-Meier curve stratified by IBD and non-IBD patients. THA patients with IBD have higher mortality compared to non-IBD THA patients (1.5 year shorter expected median survival). Solid aqua line- IBD, solid red line- non-IBD diagnosis, shaded areas- 95%
Peter Wessman (6991784)   +6 more
core   +1 more source

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