Results 221 to 230 of about 724,533 (336)

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić   +7 more
wiley   +1 more source

Colonization by Distinct Lineages, the Sundaland Barrier, and Historical Bottlenecks Shape the East-West Population Structure of <i>Avicennia</i> Mangroves Across the Indo-Pacific Interface. [PDF]

open access: yesBiology (Basel)
Phadphon P   +8 more
europepmc   +1 more source

Systematic review and scoring‐based selection of pharmacokinetic models for precision dosing of vancomycin in neonates and children

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst   +8 more
wiley   +1 more source

HLA genotype testing for carbamazepine, oxcarbazepine and eslicarbazepine: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Carbamazepine is licensed in the United Kingdom for the treatment of epilepsy, bipolar disorder and trigeminal neuralgia. The related compounds oxcarbazepine and eslicarbazepine are licensed for the treatment of epilepsy. These drugs can cause immune‐mediated hypersensitivity reactions, which typically affect the skin, and can be of variable severity ...
Lucy Galloway   +24 more
wiley   +1 more source

Developing a Thai User Interface Terminology for Systematized Nomenclature of Medicine Clinical Terms Implementation in Primary Care: Cross-Sectional Content Coverage Analysis.

open access: yesJMIR Med Inform
Tangchitnob N   +10 more
europepmc   +1 more source

Home Environmental Hazard Levels Among Community-Dwelling Older Adults Across Different Frailty States in Southern Thailand. [PDF]

open access: yesScientifica (Cairo)
Lektip C   +8 more
europepmc   +1 more source

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