KU124 (9,10,10-trioxo-N-(2-phenylphenyl)thioxanthene-3-carboxamide) as a novel inhibitor of TASK-1. [PDF]
Dumani A +36 more
europepmc +1 more source
Integration of Genetic and Imaging Data for Alzheimer's Disease Diagnosis and Interpretation
AlzCLIP is a novel contrastive learning framework that integrates single nucleotide polymorphism (SNP) profiles and MRI‐derived imaging features into a unified representation space to improve Alzheimer's disease (AD) diagnosis and interpretation. By achieving superior diagnostic accuracy and revealing key genetic and structural contributors to AD risk,
Yanfei Wang +7 more
wiley +1 more source
Water-Column Zone Impacts Non-Essential Heavy Metal Accumulation in Fish Occupying Different Zones. [PDF]
Foley M +3 more
europepmc +1 more source
Hepatic CBP/p300 Orchestrate Amino Acid‐Driven Gluconeogenesis through Histone Crotonylation
Hepatic CBP/p300 control amino acid‐driven gluconeogenesis by modulating histone crotonylation. This study identifies 2‐aminoadipate (2‐AAA) as a key metabolite that enhances crotonylation and activates amino acid and gluconeogenic gene expression.
Chunxiang Sheng +15 more
wiley +1 more source
Profiling the Impact of mGlu<sub>7</sub>/Elfn1 Protein Interactions on the Pharmacology of mGlu<sub>7</sub> Allosteric Modulators. [PDF]
Lei X +4 more
europepmc +1 more source
The formation of thallium chloride complexes and their extraction into ether
Donald L. Horrocks
openalex +2 more sources
Zur Bestimmung von Thallium in hochprozentigen Zink- und Cadmiumlaugen [PDF]
A. Kürtenacker
openalex +1 more source
Engineering Bacteria as Living Therapeutics in Cancer Therapy
Through synthetic biology approaches, natural bacteria can be genetically programmed into multifunctional living therapeutics. These engineered bacteria are capable of secreting anti‐tumor factors, displaying tumor‐associated antigens on their surface, or undergoing programmed self‐lysis to release therapeutic cargo.
Jiangfeng Chen +6 more
wiley +1 more source
Trace Elements in Post-Mortem Tissues: A Review of Current Evidence and Forensic Challenges. [PDF]
Trignano C +7 more
europepmc +1 more source

