Results 141 to 150 of about 583,007 (361)

Activation of NF‐κB Signaling by Optogenetic Clustering of IKKα and β

open access: yesAdvanced Biology, EarlyView.
This study presents an optogenetic approach for graded clustering of eGFP‐fused proteins using an eGFP‐specific nanobody and engineered Cryptochrome 2 variants. The method enables potent, reversible activation of NF‐κB signaling via endogenous pathways, as confirmed by RNA sequencing. This versatile system provides a spatially and temporally controlled
Alexandra Anna Maria Fischer   +8 more
wiley   +1 more source

2017 State-of the Science of Dispersants and Dispersed Oil (DDO) in U.S. Arctic Waters: Physical Transport and Chemical Behavior [PDF]

open access: yes, 2017
Chemical dispersants were employed on an unprecedented scale during the Deepwater Horizon oil spill in the Gulf of Mexico, and could be a response option should a large spill occur in Arctic waters. The use of dispersants in response to that spill raised
Coastal Response Research Center (CRRC)
core   +1 more source

The arctic curve of the domain-wall six-vertex model

open access: yes, 2009
The problem of the form of the `arctic' curve of the six-vertex model with domain wall boundary conditions in its disordered regime is addressed. It is well-known that in the scaling limit the model exhibits phase-separation, with regions of order and ...
A. G. Pronko   +41 more
core   +3 more sources

Double‐Stranded DNA Reduces dsRNA Degradation in the Saliva and Significantly Enhanced RNAi‐Mediated Gene Silencing in Halyomorpha halys

open access: yesAdvanced Biology, EarlyView.
The invasive pest Halyomorpha halys causes significant crop losses requiring innovative pest control strategies such as RNA interference (RNAi). However, oral RNAi is largely ineffective in H. halys. This study shows that double‐stranded DNA (dsDNA) stabilizes dsRNA in saliva by inhibiting a highly expressed nuclease.
Venkata Partha Sarathi Amineni   +2 more
wiley   +1 more source

Slow growth and high longevity characterize the common, large Arctic brittle star, Ophiopleura borealis

open access: yesFrontiers in Marine Science
The longevity (lifespan) and growth rates of a given species provide the basis for estimating its contributions to secondary production and energy flow in an ecosystem, for guiding management decisions, and determining recovery times after disturbances ...
Hanna Dinevik   +4 more
doaj   +1 more source

Hypsometry, Volume and Physiography of the Arctic Ocean and Their Paleoceanographic Implications [PDF]

open access: yes, 2003
Recent analyses of the International Bathymetric Chart of the Arctic Ocean (IBCAO) grid model include: Hypsometry (the distribution of surface area at various depths); ocean volume distribution; and physiographic provinces [Jakobsson 2002; Jakobsson et ...
Grantz, Arthur   +3 more
core   +1 more source

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

open access: yesAdvanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo   +8 more
wiley   +1 more source

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