Results 161 to 170 of about 147,399 (308)

Direct observations of atmospheric oxidized mercury speciation in polar areas. [PDF]

open access: yesNat Commun
Jokinen T   +16 more
europepmc   +1 more source

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

open access: yesAdvanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore   +20 more
wiley   +1 more source

Pan-Arctic Peatlands Have Expanded During Recent Warming. [PDF]

open access: yesGlob Chang Biol
Handley J   +21 more
europepmc   +1 more source

The Uppsala APP Mutation Promotes Wild‐Type Amyloid‐β Aggregation and Deposition In Vivo

open access: yesAdvanced Science, EarlyView.
We investigated in vivo cross‐seeding of amyloid‐β (Aβ) isoforms in transgenic mice co‐expressing wild‐typeAβ and the Uppsala‐mutant Aβ variant (AβUpp), lacking six central residues. Weleveraged MALDI‐MS imaging and hyperspectral microscopy to follow spatio‐temporalAβ deposition.
Junyue Ge   +14 more
wiley   +1 more source

A new era of bioclimatic extremes in the terrestrial Arctic. [PDF]

open access: yesSci Adv
Aalto J   +7 more
europepmc   +1 more source

Explaining the Evolution of the Arctic Council [PDF]

open access: yes, 2015
The Arctic Council is an international institution made up of the eight states that have territory in the Arctic, namely Canada, Denmark, Finland, Iceland, Norway, Russia, Sweden and the United States, as well as six indigenous peoples’ organizations.
openaire  

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

open access: yesAdvanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang   +16 more
wiley   +1 more source

Increased CH<sub>4</sub> Oxidation in Arctic Tundra Ecosystems Caused by Vegetation-Mediated Soil Drying. [PDF]

open access: yesGlob Chang Biol
Björkman MP   +8 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy