Results 31 to 40 of about 12,379 (257)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Rescue Excavations of Bronze Age Barrows in Vetrino Region, northeast Bulgaria

Materiale și Cercetări Arheologice, 2021
The aim of this study is to present the results of the rescue excavations of three Bronze Age barrows in Vetrino region, Northeast Bulgaria. Fourteen Early Bronze Age graves (4th– 3rd millennium BC), two of Middle Bronze Age date (first half of the 2nd ...
Alexandrov, S., Slavchev, V., Tonkova, E.   +2 more
doaj   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Catacomb Tribes of the Sarpa Lowland (Caspian Depression): Morphology of Long Bones and Characteristics of Physique

Oriental Studies
Introduction. The paper examines osteometric data from Middle Bronze Age Catacomb burials across the Sarpa Lowland to characterize some skeletal features and identify if there is any homogeneity degree between male and female samples.
Tatiana V. Lidzhikova
doaj   +1 more source

Features of the transformation of Late Bronze Age complexes and the problems of transition to the traditions of the Early Iron Age in the Upper Irtysh region [PDF]

Вестник археологии, антропологии и этнографии
The study of Bronze Age and Early Iron Age antiquities in the Upper Irtysh region — specifically within the mountain-steppe zone of Eastern Kazakhstan — spans more than a century.
Tkacheva N.A., Tkachev A.A.
doaj   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

Hermetic Cereal Storage in the Bronze Age

Documenta Praehistorica, 2022
The present paper explores the possibility to better understand the function of pits through phytolith and starch analysis. A case study from the Late Bronze Age/Early Iron Age settlement phase of Rotbav in southeastern Transylvania is discussed in ...
Laura Dietrich, Oliver Dietrich, Julia Meister   +2 more
doaj   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source