Results 101 to 110 of about 305,279 (357)

Inflammation, Immunity, and Cardiovascular Diseases

open access: yesMed Research, EarlyView.
Cardiovascular stress signals (e.g., hemodynamic shear, oxidized lipids, and ischemia) act on endothelial and immune cells to activate and amplify inflammation through NF‐κB, the NLRP3 inflammasome, and JAK/STAT signaling, inducing proinflammatory cytokines/chemokines (IL‐6, IL‐1β, TNF‐α, and CCL2) and self‐amplifying circuits; clinically, inflammatory
Dezhi Guo   +8 more
wiley   +1 more source

A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue

open access: yesNature Communications, 2017
Benzoxaboroles have been shown to be active against different pathogens. Here, the authors show that the benzoxaborole AN3661 inhibitsPlasmodium falciparum in vitroand in mouse models, and identify a homologue of a mammalian cleavage and polyadenylation ...
Ebere Sonoiki   +19 more
doaj   +1 more source

Genome‐Wide Assessment Reveals Ancestral Differences in Homozygosity Patterns Potentially Linked to Parkinson's Disease Etiology

open access: yesMovement Disorders, EarlyView.
Abstract Background Recessive genetic variation and extended runs of homozygosity (ROHs) may contribute to the unexplained heritability of Parkinson's disease (PD), particularly in diverse and understudied populations. Objective We conducted the first large‐scale, multi‐ancestral investigation of PD to examine the impact of genome‐wide homozygosity on ...
Kathryn Step   +680 more
wiley   +1 more source

Pour un « American Risorgimento » : cosmopolitisme et fascisme chez Ezra Pound

open access: yesL'Ordinaire des Amériques, 2017
Ezra Pound’s Cantos are an encyclopedic and polyglot work, which alludes to very different cultures, and yet is a milestone of the poetic history of the United States.
Charlotte Estrade
doaj   +1 more source

Manuel Murguía and Rosalía de Castro in her Early Stages as Narcisa Pérez Reoyo’s Work [PDF]

open access: yes
En 1865 Narcisa Pérez Reoyo publica en A Coruña su primer poemario, Cantos de la infancia, prologado por Manuel Murguía y que incluye un poema dedicado a Rosalía de Castro.
López, Teresa
core   +2 more sources

Marine litter can shift sea turtle nests toward the shoreline

open access: yesOikos, EarlyView.
Marine litter is an emerging threat to sea turtle rookeries, yet its effects on nesting behaviour remain poorly understood. In this study, we investigated how macro‐litter accumulation on beaches influences the spatial distribution of loggerhead turtle Caretta caretta nests on Boa Vista Island, Cabo Verde.
Diana Sousa‐Guedes   +4 more
wiley   +1 more source

Unveiling human–wildlife interactions in the context of livestock grazing abandonment and the return of large carnivores, ungulates and vultures: A stakeholder perspective

open access: yesPeople and Nature, EarlyView.
Abstract Pastoral practices remain a widespread economic activity across European mountain regions. However, the viability of this activity may be threatened by the recovery of large wild vertebrates associated with passive rewilding, leading to the so‐called human–wildlife conflicts.
P. Acebes   +4 more
wiley   +1 more source

W stronę modernistycznego opus vitae. Drogi twórcze Tymoteusza Karpowicza i Ezry Pounda

open access: yesAutobiografia, 2015
The article aims to present the biographies of two representatives of literary modernism in Polishand Anglo-American poetry: Tymoteusz Karpowicz and Ezra Pound. Drafting the circumstances in which their lifeworks rose (ie.
Karolina Górniak
doaj   +1 more source

Analysis of C4 Concentrations to Predict Impact of Patient‐Reported Diarrhea Associated With the Ileal Bile Acid Transporter Inhibitor Linerixibat

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 596-605, March 2025.
ABSTRACT Linerixibat, an ileal bile acid transporter (IBAT) inhibitor, is being evaluated for the treatment of pruritus in primary biliary cholangitis (PBC). Diarrhea is commonly reported with this drug class as IBAT inhibition redirects bile acids (BA) to the colon.
Fernando Carreño   +4 more
wiley   +1 more source

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