Results 171 to 180 of about 126,703,822 (285)

Reduction of CXCR3+CCR6+ CD4+ T Cells and IL‐17+ RORγt+ CD4+ T Cells During Secukinumab Treatment Identifies Patients With Axial Spondyloarthritis Responsive to Subsequent Biologic Therapy

ACR Open Rheumatology, Volume 8, Issue 9, September 2026.
Objective We recently reported an immune profile that stratifies patients with axial spondyloarthritis based on clinical response to secukinumab. We now undertake an exploratory study on the secukinumab nonresponder patients to determine if immunologic changes occur during their initial secukinumab treatment that could determine their next biologic ...
Addison Pacheco, Patricia Remalante‐Rayco, Nigil Haroon, Denis Poddubnyy, Robert D. Inman   +4 more
wiley   +1 more source

The Immunometabolic Bridge: Targeting Metainflammation to Prevent the Transition from Obesity to Cardiovascular Disease. [PDF]

J Inflamm Res
Wu M, Han Y, Liu L.
europepmc   +1 more source

3D Anodic Alumina Nanoarchitectures: A Decade of Progress from Foundational Science to Functional Metamaterials

Advanced Materials, Volume 38, Issue 51, 11 September 2026.
Ordered three‐dimensional anodic aluminum oxide (3D‐AAO) nanoarchitectures with longitudinal and transverse pores enable architecture‐driven metamaterials. The review maps fabrication advances, including hybrid pulse anodization, and shows how 3D‐AAO templates tailor properties across magnetism, energy, catalysis, and sensing.
Marisol Martín‐González
wiley   +1 more source

RBM10 modulation of circRNA biogenesis contributes to its tumor suppressor role in lung adenocarcinoma. [PDF]

Biomark Res
Utrilla-Maestre A, Matia-González AM, Peinado P, Becerra-Rodriguez MA, Benitez-Cantos MS, Cuadros M, Medina PP.   +6 more
europepmc   +1 more source

REGγ Suppresses Ferroptosis and Induces Drug Resistance by Degrading WDR6 in Chondrosarcoma

Advanced Science, Volume 13, Issue 52, 18 September 2026.
Here, we identified REGγ as a susceptibility factor in chondrosarcoma. Our study demonstrates that abnormally activated REGγ‐20S proteasome promotes chondrosarcoma development and progression. Further validation in animal models revealed that blocking REGγ function induced ferroptosis, suppressed malignant progression of chondrosarcoma, and uncovered a
Fanrong Liu, Shihui Shen, Dongxia Li, Peilin Shi, Jiaming Xu, Tongxin Lv, Yingying Du, Jingwei Zhang, Bo Yang, Hansen Chen, Zhuoya Peng, Wenjie Ren, Lu Zhang, Sheng Cheng, Tongjin Yin, Wencai Sheng, Lei Li, Juan Wu, Qingcheng Yang, Shuogui Xu, Wei Zheng   +20 more
wiley   +1 more source

The Twisted Tale of Interleukin-18 in Atherosclerosis. [PDF]

JACC Basic Transl Sci
Libby P, Nakao T.
europepmc   +1 more source

SHIP1 Restrains Hypoxia/Reoxygenation‐Induced Cytokine Secretion in Mouse Bone Marrow–Derived Mast Cells

European Journal of Immunology, Volume 56, Issue 9, September 2026.
(A) BMMCs are substantially more resistant to oxygen deprivation than neurons, microglia, oligodendrocytes, astrocytes, and fibroblasts. (B) Role of SHIP‐1 in primary mouse bone marrow mast cells’ hypoxia response. Under hypoxia, SHIP‐1 induces cytokine release. SHIP1 restrains hypoxia/reoxygenation‐induced cytokine secretion in BMMCs via the RAS/ RAF,
Lara Gubeljak, Jonas Pes, Eren Arik, Aaron T. Fehr, Mara Schietinger, Thomas Wilhelm, Sandro Capellman, Michael Huber, Pardes Habib   +8 more
wiley   +1 more source

Metformin and Weight Changes in Non-diabetic Older People With HIV (METFORAGING): A Double-Blind, Randomized, Placebo-Controlled, Pilot Trial. [PDF]

Open Forum Infect Dis
Marcelo-Calvo C, Esteban-Cantos A, Jurado F, Montejano R, Gutiérrez-García L, de Gea-Grela A, Martínez-Martín P, Díez-Vidal A, de Miguel Buckley R, Oñoro-López CM, González JC, Martín-Carbonero L, Bernardino JI, Colino RM, de Villar NGP, Rodés B, Arribas JR.   +16 more
europepmc   +1 more source

B‐Cell Remodeling and Regulatory Phenotypes During Acute COVID‐19 Are Unaffected by Polyclonal Anti‐SARS‐CoV‐2 Antibody XAV‐19

European Journal of Immunology, Volume 56, Issue 9, September 2026.
SARS‐CoV‐2 infection drives transient B‐cell remodeling toward an activated, regulatory‐like phenotype. In this randomized sub‐study, the polyclonal neutralizing antibody XAV‐19 did not detectably alter B‐cell phenotype, transcriptome, or function relative to placebo, indicating that passive polyclonal therapy preserves B‐cell homeostasis during acute ...
Nicolas Degauque, Richard Danger, Hoa Le Mai, Marion Cadoux, Thi‐Van‐Ha Nguyen, Gaëlle Tilly, François Raffi, Thomas Guimard, Karine Lacombe, Didier Laureillard, Laurent Hocqueloux, Vincent Dubee, Florence Ader, Cynthia Fourgeux, Jérémie Poschmann, Bernard Vanhove, Odile Duvaux, Benjamin Gaborit, Sophie Brouard, POLYCOR study group   +19 more
wiley   +1 more source

Revival of Ethionamide by Alpibectir. [PDF]

N Engl J Med
Pieren M, Dale GE, Gitzinger M, Tiberi S, Penman SL, Remuiñán MJ, Dubbelboer IR, Simonsson USH, Upton CM, Mabuka T, Diacon AH.   +10 more
europepmc   +1 more source