Results 161 to 170 of about 39,585 (286)

TMEM16A channel signalling microdomains in the regulation of vascular function

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley   +1 more source

Novel volume‐electron microscopic ultrastructural analysis of gastrointestinal excitability associated with calcium–activated chloride channels

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Immunohistochemistry, electrophysiology and pharmacology are useful tools for understanding protein and channel expression and physiological reactions of calcium‐activated chloride channels (CaCCs). Conventional transmission electron microscopy has provided useful 2‐D information on organelle arrangement, localization and ...
Hiromi Tamada
wiley   +1 more source

Update on cellular expression and function of ANO1 channels in urethral smooth muscle

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Activation of ANO1 channels and resulting Cl− efflux are suggested to modulate urethral smooth muscle contractility by enhancing Ca2+ influx via voltage‐dependent Ca2+ entry and resulting contraction in urethral smooth muscle cells.
Bernard T. Drumm, Neha Gupta
wiley   +1 more source

Three-Point Compact Approximation for the Caputo Fractional Derivative

open access: yes, 2015
In this paper we derive the fourth-order asymptotic expansions of the trapezoidal approximation for the fractional integral and the $L1$ approximation for the Caputo derivative. We use the expansion of the $L1$ approximation to obtain the three point compact approximation for the Caputo derivative \begin{equation*} \dfrac{1}{ (2- )h^ }\sum_{k=0}^{n}
openaire   +2 more sources

Evaluation of Enzyme Inhibition and Kinetic Profiles of Origanum Essential Oils on Metabolic and Central Nervous System Targets

open access: yesNatural Sciences, Volume 6, Issue 3, July 2026.
The essential oils of three Origanum species were chemically characterized and evaluated for their antioxidant and enzyme inhibitory activities. The different compositions confer selective bioactivities: O. vulgare exhibits good antioxidant and α‐glucosidase inhibitory activity, O. majorana shows promising tyrosinase inhibition, and O.
Giuseppe Amato   +6 more
wiley   +1 more source

The Rise of Human–Computer Integration in Marketing: A Theory Synthesis

open access: yesPsychology &Marketing, Volume 43, Issue 6, Page 1343-1380, June 2026.
ABSTRACT Human–computer integration (HCInt) technologies, which merge human bodily, cognitive, and sensory functions with computational processes, are reshaping the foundations of consumer experience. Unlike traditional human–computer interaction, HCInt entails adaptive and reciprocal coupling through AI‐driven augmentation, wearables, muscle–computer ...
Carlos Velasco   +5 more
wiley   +1 more source

Highly Lewis Acidic In Situ‐Generated Boronic Acid Ester: A Practical Catalyst for Hosomi–Sakurai Conjugate Addition, Carbonyl‐Ene Reaction, and Silane‐Mediated Amide Reduction

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 9, 5 May 2026.
An exceptionally Lewis acidic boronic acid ester, generated in situ from pentafluorophenylboronic acid and tetrabromonaphthalenediol, catalyzes three important chemical transformations at 1–10 mol% loading: the Hosomi–Sakurai allylation of α,β‐unsaturated ketones, intermolecular carbonyl‐ene reactions, and the reductions of tertiary amides to amines ...
Ava Bousselat   +5 more
wiley   +1 more source

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