Results 31 to 40 of about 583,418 (264)

Impact of Japan's 2024 Physician Work‐Style Reform on Pediatric Hematology–Oncology: Educational Implications in a 2‐Year Survey

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Japan's 2024 physician work‐style reform introduced legally binding limits on physicians’ working hours, but its impact on education and workforce sustainability in pediatric hematology–oncology (PHO) remains unclear. Procedure We conducted a repeated cross‐sectional study with structured quantitative items and free‐text responses ...
Kiyohiko Kaizu   +7 more
wiley   +1 more source

أثر السياق في توجيه متشابه القرآن عند الإمام الكرماني

open access: yesمجلة الآداب و العلوم الإجتماعية, 2016
This study discusses the importance of context in the explanation and interpretation of similar compositions verbally in the Koran، and the results achieved Aque Imam al-Kirmani had a clear approach in the treatment of Koranic similar compositions، it ...
فضيلة عظيمي
doaj  

RHETORIC IN THE CONTEXT OF THE POST-TRUTH SITUATION

open access: yesЕпістемологічні дослідження у філософії, соціальних і політичних науках
This article analyzes the origins and significance of rhetoric as an effective means of control through modal power exercised by free citizens of the classical Athenian polis.
Вадим ПАЛАГУТА
doaj   +1 more source

Prospects for the government of Pedro Sanchez in the context of socio-political situation in Spain

open access: yesИбероамериканские тетради, 2022
The left and the right parties in modern Spain often approach many problems that the country faces very differently. In these conditions, the question of whether the left-wing coalition government led by Pedro Sánchez will remain in power until the end ...
S. M. Khenkin
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

New opportunities for the Russian Baltic exclave in the context of changes in the country’s geopolitical situation

open access: yesBaltic Region, 2022
Current geopolitical and geoeconomic changes require a reconsideration of the role of the Kaliningrad region in the Baltic region. This study aims to demonstrate the possible effect of some trends in the development of the neighbouring countries on the ...
Vyacheslav A. Shuper
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Polish individual restrictive measures applied to economic entities in the context of the war in Ukraine and the situation in Russia and Belarus

open access: yesTerroryzm
Poland, like several other European Union countries, adopted restrictive measures in response to the Russian Federation’s aggression against Ukraine in 2022, as well as serious human rights violations
Mariusz Cichomski, Konrad Kaczor
doaj   +1 more source

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