Results 61 to 70 of about 179,545,467 (248)
FEBS Open Bio, EarlyView.Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
Digital Requests for Academic Help: the Context of Situation
The ESPecialist, 2013 Digital genres usually present features which have not been crystallized. Nevertheless, by means of principles of Genre Analysis (Swales, 1990, 1992; Bhatia, 1993, 2004) and concepts from Systemic-Functional Grammar (Halliday, 1970, 1989; Halliday ...
Rosângela Ávila Dantas
doaj
Comorbid Tuberculosis in the Context of the Formation of a Local Epidemic Situation
Антибиотики и ХимиотерапияThe aim of the study was to analyze epidemiological data on tuberculosis in the Kursk region, taking into account the changing socio-economic situation in the region, as well as to study the possibilities of using remaxol in the regimens of accompanying ...
V. M. Kolomiets +5 more
doaj +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Biennial report of the Comptroller of the State of Connecticut to the General Assembly
, 1891 Biennial; -1894.; Report year end varies: it ends June 30 from 188 -1890; it ends Sept.
Connecticut. Office of the State Comptroller.
core
, 1992 The news report for the 21/10/1992 is pre-empted after two minutes of play. The broadcast then jumps to the report for the 23/10/1992.
The British Broadcasting Corporation
core +1 more source
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley +1 more source
The Situation of Buddhists Buryatia in the Context of the Liberalization of Soviet Religious Policy
Журнал Фронтирных ИсследованийBased on the materials of the State Archive of the Russian Federation and the State Archive of the Republic of Buryatia, the article examines the activities of the Buddhists of Buryatia in the second half of the 1980s.
Petr K. Dashkovskiy, Egor A. Traudt
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk +10 more
wiley +1 more source