Introduction. The article examines the peculiarities of the formation and functioning of the international legal mechanism for protecting children’s environmental rights at the international universal level within the framework of the United Nations. The
Ihor Voievodin
doaj +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
The Domestication of the United Nations, Convention on the Rights of the Child in South Africa
The domestication of the United Nations Convention on the Rights of the Child (CRC) in South Africa presents a critical constitutional commitment towards protecting the rights of children.
Raymond Chirowamhangu, Ruth Nyamadzawo
doaj +1 more source
Why the USA should ratify the UN Convention on the Rights of the Child. [PDF]
Lichtsinn H, Goldhagen J.
europepmc +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Ergenlerin Çocuk Hakları Hakkındaki Görüşlerinin İncelenmesi
Amaç: “Çocuk Hakları” çocukların doğumdan itibaren sahip oldukları; ırk, dil, din, cinsiyet ya da toplumsal farklılıkları kabul etmeden sahip olunan ve çocukların yüksek yararını korumayı amaçlayan haklardır.
Zehra Eriş, Figen Gürsoy, Nur Sena Öz
doaj
Comparative Study of the Right to Education of Children from the perspective of the Convention on the Rights of the Child and the Constitutional Law of Iran [PDF]
The right to education is one of the basic and fundamental rights that is considered among the basic human rights. This right has been emphasized at the global level under conventions, international covenants, the Universal Declaration of Human Rights ...
Milad Kashi Komijani, mahdi rajaei
doaj +1 more source
What does the best interests principle of the convention on the rights of the child mean for paediatric healthcare? [PDF]
März JW.
europepmc +1 more source
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source

