Results 141 to 150 of about 1,013,192 (302)
Co‐Occurring Non‐Cardiac Congenital Anomalies Among Cases With Congenital Heart Defects
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Cases with congenital heart defects (CHD) often have other associated anomalies. The aim of this investigation was to assess the prevalence and the types of co‐occurring anomalies in CHD in a well‐defined population. The anomalies co‐occurring with CHD were ascertained in all live births, stillbirths and terminations of pregnancy for fetal ...
Claude Stoll +2 more
wiley +1 more source
Multicomponent Stapling of Glucagon‐Like Peptide‐1 Enables Receptor‐Guided PROTAC Delivery
Angewandte Chemie, EarlyView.We report a stapled glucagon‐like peptide‐1 (GLP‐1) analogue created via multicomponent tryptophan‐mediated Petasis reaction (TMPR). This strategy yields a stabilised peptide with superior helicity and improved potency. Conjugation to a bromodomain‐containing protein 4 (BRD4) degrader creates the first GLP‐1‐guided targeted protein degrader (PROTAC ...
Jan L. Venne +5 more
wiley +2 more sources
The Use of Structural Funds for Enterprise Competitiveness Growth in the Czech Republic
The competitiveness of enterprises depends not only on their strategies and operations but also on the macroeconomic and microeconomic environment in which they operate.
Skokan, Karel
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Inflationary Bias in Mid to Late Transition Czech Republic [PDF]
A series of studies confirm results presented Filer and Hanousek (2000) suggesting that mismeasurement of inflation during the transition is a serious problem, on the same relative order of magnitude (and greater in absolute magnitude) as in advanced ...
Jan Hanousek, Randall K. Filer
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Australian Journal of Social Issues, EarlyView.ABSTRACT The Australian paid parental leave (PPL) government scheme aims to support working parents through financial assistance and the promotion of gender equality in caregiving responsibilities. However, the scheme's implementation has been critiqued for its gendered design, which marginalises fathers and reinforces traditional gender roles.
Lily Lewington +2 more
wiley +1 more source
Health Care in the Czech Republic, Hungary and Poland - the medium term fiscal aspects [PDF]
The paper provides perspective of recent developments in health care reforms in three fast-reforming transition economies: the Czech Republic, Hungary and Poland.
Peter Mihalyi, Ryszard Petru
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Translation and Cross‐Cultural Adaptation of the Chronic Rhinosinusitis Control Test for Global Use
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Introduction The Chronic Rhinosinusitis Control Test (CRCT) is a patient‐reported outcome measure (PROM) written in English that is psychometrically validated to measure chronic rhinosinusitis control. Because the availability of translated PROMs is a driver of data equity—collection of data that is fair and generally representative—our ...
Hye K. Pae +52 more
wiley +1 more source
Liquidity Effects and Precautionary Saving in The Czech Republic [PDF]
Since the break up of the Czech-Slovak Federation on 31 December 1992, the Czech Republic has been at the forefront of the transition to a market economy.
Cuthbertson, Keith, Bredin, Don
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Annals of Neurology, EarlyView.Objective Dysarthria is one of the most common and disabling side effects of subthalamic nucleus deep brain stimulation (STN‐DBS) in Parkinson's disease (PD). Stimulation often exacerbates speech dysfunction beyond the effects of PD progression, likely because of current spread to structures surrounding the STN.
Petr Krýže +17 more
wiley +1 more source
The Public Pension System in the Czech Republic from the Point of View of Public Finance [PDF]
The Czech public pension system is fiscally unsustainable in the long run because of population ageing, which is particularly pronounced in the Czech Republic.
Bezdek, Vladimir
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