Results 41 to 50 of about 145,460,026 (308)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Learning Indoor Environment for Effective LiFi Communications: Signal Detection and Resource Allocation

open access: yesIEEE Access, 2022
Seamless light fidelity (LiFi) communications in a realistic indoor environment faces a number of important challenges including the loss of line-of-sight (LOS) link due to the random orientation of mobile devices or blockage by users or furniture in the
Nurul Aini Amran   +3 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Errata to Sound Hashing Modes of Arbitrary Functions, Permutations, and Block Ciphers

open access: yesIACR Transactions on Symmetric Cryptology, 2020
In ToSC 2018(4), Daemen et al. performed an in-depth investigation of sound hashing modes based on arbitrary functions, permutations, or block ciphers. However, for the case of invertible primitives, there is a glitch.
Aldo Gunsing, Joan Daemen, Bart Mennink
doaj   +1 more source

Digital Collections and Digital Collecting Practices [PDF]

open access: yesProceedings of the 33rd Annual ACM Conference on Human Factors in Computing Systems, 2015
Reference is increasingly made to ‘digital collections’, yet this term encompasses accumulated digital objects of varying form, purpose and value. We review social science literature on mate-rial collections and draw from in-depth interviews with 20 peo-ple in the UK in order to offer a clearer understanding of what constitutes a digital collection and
Rebecca D. Watkins   +2 more
openaire   +2 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

From the Digitized to the Digital Library

open access: yesD-Lib Magazine, 2001
Historical Social Research.
openaire   +3 more sources

Digital (In)Equality, Digital Inclusion, Digital Humanism

open access: yes12th ACM Conference on Web Science Companion, 2020
From its inception, the World Wide Web has been intended to be a force for social good. But there are many barriers and obstacles, a situation commonly characterized as the Digital Divide. Several billion people especially in the Global South do not have access to Internet/Web for reasons of lacking (affordable) infrastructure, poverty, low literacy ...
Anna Bon, Hans Akkermans
openaire   +3 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Digital Transformation and Digital Leadership [PDF]

open access: yesHealthcare Informatics Research, 2019
Healthcare does not transform itself; it is transformed by us. The people coming to the Biomedical Informatics society are those who wish to make changes. In my opinion, this is what digital leadership is. Through this article, I will share what is happening in the world around us in terms of Biomedical Informatics.
openaire   +3 more sources

Home - About - Disclaimer - Privacy