Results 71 to 80 of about 155,282,009 (302)
Introduction - Platforms and Infrastructures in the Digital Age
Information systems research, 2018 In the last few years, leading-edge research from information systems, strategic management, and economics have separately informed our understanding of platforms and infrastructures in the digital age.
P. Constantinides +2 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Massively parallel digital transcriptional profiling of single cells
Nature Communications, 2016 Characterizing the transcriptome of individual cells is fundamental to understanding complex biological systems. We describe a droplet-based system that enables 3′ mRNA counting of tens of thousands of single cells per sample.
Grace X. Y. Zheng +32 more
semanticscholar +1 more source
Family visits to libraries and bookshops: observations and implications for digital libraries [PDF]
, 2014 This paper explores how families select books for leisure reading. We recruited 17 families (adults and children) for this study, and spent time with each in both bookshops and public libraries.
Sally Jo Cunningham +7 more
core +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Can technology increase COVID-19 vaccination rates?
The Lancet: Digital Health, 2021 The Lancet Digital Health
doaj +1 more source
Algorithmic governmentality: radicalisation and immune strategy of capitalism and neoliberalism? [PDF]
La Deleuziana, 2016 This article is a set of reflections on the question: ‘what is completely new in algorithmic governmentality compared to capitalism and neoliberalism?’ The following text is thus some preliminary, temporary and definitively uncertain intuitions in ...
Antoinette Rouvroy
doaj
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
Bioinform., 2009 Summary: It is expected that emerging digital gene expression (DGE) technologies will overtake microarray technologies in the near future for many functional genomics applications.
Mark D. Robinson +2 more
semanticscholar +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
La gouvernementalité algorithmique : radicalisation et stratégie immunitaire du capitalisme et du néolibéralisme ? [PDF]
La Deleuziana, 2016 This article is a set of reflections on the question: ‘what is completely new in algorithmic governmentality compared to capitalism and neoliberalism?’ The following text is thus some preliminary, temporary and definitively uncertain intuitions in ...
Antoinette Rouvroy
doaj