Results 41 to 50 of about 2,053,928 (267)
Abstract When discussing the Middle East’s digital turn, it is essential to recognize inherent disjunctures between the predigital and the digital: between “old” media that clings to print publications, radio stations, and satellite television and “new” media that embraces and promotes the use of software, portals, social media, and ...
Mohamed Zayani, Joe F. Khalil
openaire +1 more source
Digital Transformation and Digital Leadership [PDF]
Healthcare Informatics Research, 2019 Healthcare does not transform itself; it is transformed by us. The people coming to the Biomedical Informatics society are those who wish to make changes. In my opinion, this is what digital leadership is. Through this article, I will share what is happening in the world around us in terms of Biomedical Informatics.
openaire +3 more sources
Digital humanities and digital social reading [PDF]
Digital Scholarship in the Humanities, 2019 Abstract Prominent among the social developments that the web 2.0 has facilitated is digital social reading (DSR): on many platforms there are functionalities for creating book reviews, ‘inline’ commenting on book texts, online story writing (often in the form of fanfiction), informal book discussions, book vlogs, and more.
Simone Rebora +10 more
openaire +5 more sources
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
La governamentalità algoritmica: radicalizzazione e strategia immunitaria del capitalismo e del neoliberalismo? [PDF]
La Deleuziana, 2016 This article is a set of reflections on the question: ‘what is completely new in algorithmic governmentality compared to capitalism and neoliberalism?’ The following text is thus some preliminary, temporary and definitively uncertain intuitions in ...
Antoinette Rouvroy
doaj
Computing Logarithms Digit-by-Digit
BRICS Report Series, 2004 In this work, we present an algorithm for computing logarithms of positive real numbers, that bares structural resemblance to the elementary school algorithm of long division. Using this algorithm, we can compute successive digits of a logarithm using a 4-operation pocket calculator.
openaire +2 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
BMC Medical Informatics and Decision Making, 2023 Background There are many Machine Learning (ML) models which predict acute kidney injury (AKI) for hospitalised patients. While a primary goal of these models is to support clinical decision-making, the adoption of inconsistent methods of estimating ...
Amir Kamel Rahimi +6 more
doaj +1 more source