Results 131 to 140 of about 155,282,009 (302)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Leaving cancer diagnosis to the computers

The Lancet: Digital Health, 2020
The Lancet Digital Health
doaj   +1 more source

Metaphorically Speaking: Possibilities of Theatre Performance in the Digital Age

Caracteres: Estudios Culturales y Críticos de la Esfera Digital, 2012
This essay reflects on the quality of the theatre performance as medium in the digital age through a discussion of the theatre of Peter Handke. The aim is to make manifest and engage with habits of thought and perception shaped by the digital, as well as
Ioana Juncan
doaj  

Digital media exposure and pediatric health: the recommendations from the Italian Society of Pediatrics Digital Dependency Commission

Italian Journal of Pediatrics
Background Digital media exposure has become an integral component of childhood and adolescence, profoundly reshaping developmental environments worldwide.
Elena Bozzola, Mariangela Irrera, Sarah Barni, Cinthia Caruso, Bianca Leccese, Enrica Franzese, Lavinia Fioretti, Luca Bernardelli, Elena Scarpato, Vita Cupertino, Teresa Mazzone, Rocco Russo, Alfonso Benevento, Barbara Strappato, Marco Cervellini, Pietro Ferrara, Rino Agostiniani   +16 more
doaj   +1 more source

Measuring the Impact of Preserving Digital Assets [PDF]

, 2012
This presentation discusses measuring the impact of preserving digital assets. This presentation reports the initial findings of a study of the impact of digitizing assets, specifically: (a) a framework of impact areas and indicators and (b) findings for
Belden, Dreanna, Murray, Kathleen R.
core  

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Development of an evidence-based evaluation framework for digital health software products

Scientific Reports
Current frameworks and standards for evaluation of digital health software products (DHSPs) are fragmented and may not cover the spectrum of what stakeholders consider most important.
Jennifer C. Goldsack, Colby Holliday, Yashoda Sharma, Doug Mirsky, Cole Zanetti, Benjamin Vandendriessche   +5 more
doaj   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Digital health equity for older populations

The Lancet: Digital Health, 2023
The Lancet Digital Health
doaj   +1 more source

Multi-Scale Geometric Feature Extraction and Global Transformer for Real-World Indoor Point Cloud Analysis

Mathematics
Indoor point clouds often present significant challenges due to the complexity and variety of structures and high object similarity. The local geometric structure helps the model learn the shape features of objects at the detail level, while the global ...
Yisheng Chen, Yu Xiao, Hui Wu, Chongcheng Chen, Ding Lin   +4 more
doaj   +1 more source